Hydrogen Bonding and Catalysis: A Novel Explanation for How a Single Amino Acid Substitution Can Change the pH Optimum of a Glycosidase

Author: Joshi M.D.   Sidhu G.   Pot I.   Brayer G.D.   Withers S.G.   McIntosh L.P.  

Publisher: Academic Press

ISSN: 0022-2836

Source: Journal of Molecular Biology, Vol.299, Iss.1, 2000-05, pp. : 255-279

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Abstract