Description
Founded in 1959, by John Kendrew, the Journal of Molecular Biology was the first journal devoted to this new and revolutionary science. To celebrate the thirtieth anniversary of the Journal, the current editor, Sydney Brenner, has selected a number of papers from the first hundred volumes. They include the seminal papers on genetic regulation by Jacob and Monod and on allostery by Monod, Changeux and Jacob. Also included are many important papers on structural biology and molecular genetics and papers reflecting the initial developments in DNA cloning and sequencing.
Of value to all biologists with an interest in the molecular basis of living systems, the book is a personal selection by the Editor. Readers are encouraged to compare it with their own choice from the Journal of Molecular Biology.
Chapter
Chapter 3. Structural Components of Bacteriophage
pp.:
39 – 64
Chapter 4. Molecular Homogeneity of the Deoxyribonucleic Acid of Phage T2
pp.:
64 – 74
Chapter 5. Structural Considerations in the Interaction of DNA and Acridines
pp.:
74 – 89
Chapter 6. The Theory of Mutagenesis
pp.:
89 – 93
Chapter 7. Genetic Regulatory Mechanisms in the Synthesis of Proteins
pp.:
93 – 132
Chapter 8. The Formation of Hybrid DNA Molecules and their use in Studies of DNA Homologies
pp.:
132 – 157
Chapter 9. An Estimate of the Length of the DNA Molecule of T2 Bacteriophage by Autoradiography
pp.:
157 – 164
Chapter 10. An Active Cistron Fragment
pp.:
164 – 169
Chapter 11. Host Specificity of DNA Produced by Escherichia Coli
pp.:
169 – 188
Chapter 12. The Bacterial Chromosome and its Manner of Replication as seen by
Autoradiography
pp.:
188 – 197
Chapter 13. Allosteric Proteins and Cellular Control Systems
pp.:
197 – 221
Chapter 14. Hybrid Protein Formation of E. coli Alkaline Phosphatase Leading to in vitro
Complementation
pp.:
221 – 234
Chapter 15. Electron Microscope Studies on the Structure of Natural and Synthetic Protein
Filaments from Striated Muscle
pp.:
234 – 293
Chapter 16. N-Formyl-methionyl-S-RNA
pp.:
293 – 301
Chapter 17. On the Mechanism of Genetic Recombination between DNA molecules
pp.:
301 – 313
Chapter 18. An Optical Method for the Analysis of Periodicities in Electron Micrographs,
and Some Observations on the Mechanism of Negative Staining (1964)
pp.:
313 – 320
Chapter 19. The Detachment and Maturation of Conserved Lambda Prophage DNA
pp.:
320 – 327
Chapter 20. Molecular Consequences of the Amber Mutation and its Suppression
pp.:
327 – 342
Chapter 21. A Two-dimensional Fractionation Procedure for Radioactive Nucleotides
pp.:
342 – 372
Chapter 22. Ochre Mutants, a New Class of Suppressible Nonsense Mutants
pp.:
372 – 381
Chapter 23. Codon–Anticodon Pairing: The Wobble Hypothesis
pp.:
381 – 389
Chapter 24. Specificity of sRNA for Recognition of Codons as Studied by the Ribosomal
Binding Technique
pp.:
389 – 407
Chapter 25. Structure of Viruses of the Papilloma-Polyoma Type. IV:† Analysis of Tilting Experiments in the Electron Microscope
pp.:
407 – 426
Chapter 26. Structure of Crystallin α-Chymotrypsin II.† A Preliminary Report Including a Hypothesis for the Activation Mechanism
pp.:
426 – 449
Chapter 27. Mutant Tyrosine Transfer Ribonucleic Acids
pp.:
449 – 466
Chapter 28. A General Method Applicable to the Search for Similarities in the Amino Acid
Sequence of Two Proteins
pp.:
466 – 477
Chapter 29. A Restriction Enzyme from Hemophilus influenzae. II Base Sequence of the Recognition Site
pp.:
477 – 494
Chapter 30. Calcium-dependent bacteriophage DNA Infection
pp.:
494 – 498
Chapter 31. Repeating Sequences and Gene Duplication in Proteins
pp.:
498 – 519
Chapter 32. Studies on Polynucleotides† CIII.‡ Total Synthesis of the Structural Gene for an Alanine Transfer Ribonucleic Acid from Yeast
pp.:
519 – 544
Chapter 33. Enzymatic End-to-end Joining of DNA Molecules
pp.:
544 – 565
Chapter 34. Site-directed Mutagenesis: Generation of an Extracistronic Mutation in
bacteriophage Qβ RNA
pp.:
565 – 586
Chapter 35. Molecular Structure Determination by Electron Microscopy of Unstained
Crystalline Specimens
pp.:
586 – 608
Chapter 36. A Rapid Method for Determining Sequences in DNA by Primed Synthesis
with DNA Polymerase
pp.:
608 – 618
Chapter 37. Detection of Specific Sequences Among DNA Fragments Separated by Gel
Electrophoresis
pp.:
618 – 636