Chapter
The Inflammatory Response
Immunopathology (the Double-Edged Sword)
2 Cells of the Immune System
The Blood and Lymphoid Systems
Cellular Interactions in Immune Responses
Hematopoiesis (Blood Formation)
3 Inflammation and Wound Healing
The Cells of Acute Inflammation
Adult Respiratory Distress Syndrome
Interrelationships of Inflammatory Cells and Protein Systems in Acute Inflammation
The Cells of Chronic Inflammation
Cytokines in Chronic Inflammation
Review of Mediators of Inflammation
Manifestations of Inflammation in Tissues
Cytokines, Adhesion Molecules, and Growth Factors in Atherosclerosis
Antibody-Antigen Reactions
The B-Cell Receptor (BCR)
Gene Rearrangements in Lymphomas and Leukemias
Application of Antibody Technology to Therapy
5 All about T Cells and Induction of Immunity
T Cells and the Immune Response
The Lymphatic System: Vessels and Organs
Lymphoid Organs: Structure and Function
Development of Lymphoid Organs (Ontogeny)
II Immunopathology and Immunity
7 Introduction to Part II
Immunity, Immunopathology, Hypersensitivity, and Allergy
Immune Effector Mechanisms
The “Double-Edged Sword” of Immune Defense Mechanisms
8 Inactivation and Activation of Biologically Active Molecules
Mechanisms of Antibody-Mediated Inactivation and Activation
Examples of Antibody-Mediated Inactivation and Activation
Ligands, Receptors, and Idiotypes
Neutralizing Antibodies: Cause and Effect
Protective Functions of Inactivating (Neutralizing) Antibodies
9 Cytotoxic and Cytolytic Reactions
The Mechanism of Cytolytic Reactions
Immunohematologic Diseases
Other Cytotoxic Reactions
Detection of Circulating Cytotoxic Antibodies
Protective and Pathologic Effects in Infectious Diseases
10 Immune Complex Reactions
Immune Complexes in Infectious Diseases
Diffuse Connective Tissue Diseases
Other Immune Complex Diseases
Evaluation of Circulating Immune Complexes
11 Atopic and Anaphylactic Reactions (Allergy)
Immunotherapeutic Modification of Atopic Allergy
Pharmacologic Control of Atopic Reactions
Chapter 12 T-Cell-Mediated Cytotoxicity
TCTL, TDTH, and Natural Killer Cells
Induction of T-Cell Immunity
TCTL-Cell Reactions In Vitro
TCTL-Cell Reactions In Vivo
13 Delayed-Type Hypersensitivity TDTH
TDTH-Cell Reactions: Delayed-Type Hypersensitivity
TDTH-Cell Activation and Superantigens
Delayed-Type Hypersensitivity Skin Reaction
Cutaneous Basophil Hypersensitivity
Delayed-Type Hypersensitivity and Infection
TDTH-Cell-Mediated Autoimmune Disease
TCTL and TDTH Cells, Tuberculosis, and Leprosy
14 Granulomatous Reactions
15 Interplay of Inflammatory and Immunopathologic Mechanisms, Immune Defense, and Evasion of Immune Defense Mechanisms during Infection
Interaction of Immune and Nonimmune Inflammation
Immune-Specific Protection against Infection
Interaction of Immune Mechanisms in Some Infectious Diseases
Evasion of Immune Defense Mechanisms
16 Immune-Mediated Skin Diseases
Inactivation or Activation
Cytotoxic or Cytolytic Reactions
17 Immunoproliferative Diseases
Maturation of Blood-Forming Cells and Leukemia
Lymphoid Tissue Structure and Lymphoproliferative Disease
Nonmalignant Lymphoproliferation
Infections Associated with Lymphoproliferative Diseases
18 Immunodeficiency Diseases
Immune Deficiencies and Infections
Primary Immunodeficiencies
Secondary Immunodeficiencies
Evaluation of Immunodeficiency
Human Immunodeficiency Virus
History of Tumor Immunity
Evidence for Tumor Immunity in Humans
Carcinogenesis and Tumor Immunity
Mechanisms of Tumor Cell Destruction by the Immune System
Immunodiagnosis of Cancer
Appendix 1 History of Immunopathology
Appendix 2 Evolution of Immunity (Phylogeny)
Appendix 3 Cluster-of-Differentiation Molecules
Appendix 5 Clinical Immunology Tests
Appendix 6 Tables of Lymphoproliferative
Diseases
Immunology, Immunopathology, and Immunity, Sixth Edition
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