Biochemistry, Biosynthesis and Human Diseases
：Volume 2: Biochemistry, Biosynthesis and Human Diseases
Publication subTitle ：Volume 2: Biochemistry, Biosynthesis and Human Diseases
Author： Rouault Tracey;Maio Nunziata;Dos Santos Patricia
Publisher： De Gruyter
Publication year： 2017
E-ISBN: 9783110479850
P-ISBN(Paperback): 9783110479393
Subject： Q51 Protein
Keyword： 无机化学,分子生物学,微生物学,生物化学
Language： ENG
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Description
This volume on iron-sulfur proteins includes chapters that discuss how microbes, plants, and animals synthesize these complex prosthetic groups, and why it is important to understand the chemistry and biogenesis of iron sulfur proteins. In addition to their vital importance in mitochondrial respiration, numerous iron sulfur proteins are important in maintenance of DNA integrity. Multiple rare human diseases with different clinical presentations are caused by mutations of genes in the iron sulfur cluster biogenesis pathway. Understanding iron sulfur proteins is important for understanding a rapidly expanding group of metabolic pathways important in all kingdoms of life, and for understanding processes ranging from nitrogen fixation to human disease.
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