Biomaterials for Bone, Regenerative Medicine

Author： Sooraj Hussain Nandyala; Santos José D.  

Publisher： Trans Tech Publications‎

Publication year： 2010

E-ISBN: 9783038134428

P-ISBN(Paperback): 9780878491537

Subject： R318.08 Biological Materials

Keyword： 工程材料学

Language： ENG

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Description

Volume is indexed by Thomson Reuters BCI (WoS).The aim of “Biomaterials for Bone Regenerative Medicine” is to review extensively the latest developments in Biomaterials and their application to bone regeneration in vivo. Indeed, research on biomaterials and their novel applications is essential because of the health issues related to the aging population. A wide range of worldwide investigations is being undertaken by eminent scholars in order to develop further innovative materials for next-generation applications. In future, it is expected that a tissue engineering approach, associating novel biomaterials with stem cells, will be available for all types of bone defect. This book is the result of a collaborations between active research groups having expertise in the hottest field of bone-tissue regeneration and reconstruction. It concisely covers materials ranging from the nano-scale to the macroscopic, and offers a comprehensive description of the subject for newcomers, as well as for professionals who may be somewhat unfamiliar with the ceramic aspects of the applications. Biomaterial engineers and related specialists, a surprising number from Portugal, review recent research into the biomaterials used not only as components in regenerated bone, but also for other functions in the process of bone regeneration. They cover skeletal regenerative biomaterials, silica-based materials as precursors of nano-apatites, phytochemicals for bone regeneration, designe

Chapter

Biomaterials for Bone, Regenerative Medicine

Dedicated

Contents

Forward

Preface

Contributors

Table of Contents

CHAPTER 1 Skeletal Regenerative Nanobiomaterials

1. Introduction

2. Basics of Bone Biology

3. Current Scenarios of Bone Grafting

4. Concept of Biomimetics in Skeletal Regeneration

5. Mechanism of Biological Mineralization

6. Biomimetic Mineralization – Rationale and Benefits

7. Processing of Biomineralized Nanobiomaterial Systems

8. Biomineralization of Electrospun Nanofibers – A New Approach

Conclusions and Future Challenges

Glossary

References

CHAPTER 2 Silica-Based Materials as Precursorsof Nanoapatites

1. Bioactive glasses

2. Sol-Gel Glasses: Components of Mixed Materials

3. Organic-Inorganic Hybrids to Expand the Clinical Application of Bioactive Glasses

4. Star Gels Bioactive Materials

5. Silica Based Ordered Mesoporous Materials

6. Synthesis of Templated Glasses

7. Considerations on Materials Eligible for Bone Regeneration Duties

References

CHAPTER 3 Phytochemicals for Bone Regeneration

1. Introduction

2. Material and Methods

3. Results

4. Discussion

5. Conclusion

References

CHAPTER 4 Designed Biomaterial Scaffoldsfor Bone Regeneration

1. Introduction

2. Scaffold Design

3. Effective Mechanical and Permeability Properties of Designed Scaffolds

4. Bone Regeneration on Designed Scaffolds

5. Discussion

References

CHAPTER 5 Engineered Ca-Si Based Ceramics for Skeletaltissue Reconstruction

1. Introduction

2. Ca-Si Based Bioactive Glass and Glass-Ceramics

3. Ca-Si Based Binary Oxide System Bioactive Ceramics

4. Ca-Si-Mg Bioactive Ceramics

5. Future Trends. References

CHAPTER 6 Calcium Phosphate-Based Materials for Boneregenerative Medicine

1. Introduction

2. Bioactive Glasses and Glass-Ceramics

3. Silicon-Substituted Apatites

4. Calcium Phosphate-Based Materials

5. Bonelike® Medical Applications

References

CHAPTER 7 Cell Adhesion and Proliferation over Zinc-Glassreinforced Hydroxyapatite Composites (Zn-GRHA)

1. Introduction

2. Materials and Methods

3. Physicochemical and Morphological Analysis of the Zn-GRHA Composites

4. In Vitro Biocompatibility of the Zn-GRHA Composites

5. Conclusions. References

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