Molecular Modelling-Based Investigations of a Mutant Protein in Patients with Hearing Loss ( Pharmacology and Therapeutics )

Publication series ： Pharmacology and Therapeutics

Author： Kazunori Namba  

Publisher： IntechOpen‎

Publication year： 2014

E-ISBN: INT5708558398

P-ISBN(Paperback): 9789535116202

P-ISBN(Hardback):  9789535116202

Subject： R47 Nursing

Keyword： 护理学

Language： ENG

Access to resources Favorite

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Molecular Modelling-Based Investigations of a Mutant Protein in Patients with Hearing Loss

Chapter

Chapter 1 Molecular Modelling-Based Investigations of a Mutant Protein in Patients with Hearing Loss

1. Introduction

2. The voltage-gated potassium channel KCNQ4

3. Materials and methods

3.1. Genetic analysis

3.2. Molecular modelling of KCNQ4

4. Results and discussion

4.1. p.Y270H mutation

4.2. p.Ser269del mutation

4.3. p.G285S and p.G287R mutations

5. Conclusion

Author details

References

The users who browse this book also browse