Description
Staphylococci remain the most important cause of hospital-acquired infections in the U.S. and MRSA has become the most common cause of skin and soft tissue infection in many parts of the world.
There is now a much greater understanding of the physiology and evolution of the staphylococci and this new edition reflects the rapid advancements in knowledge about this pathogen and provides a comprehensive review from both clinical and basic science perspectives.
The first section addresses the basic biology of the staphylococci, their molecular genetics, host defenses and host evasion, virulence determinants, mechanisms of antibiotic resistance, and laboratory techniques. The second section deals with epidemiology, and the third section provides an overview of the varied clinical manifestations of human staphylococcal infections. The fourth section covers prevention and treatment of these often life-threatening infections.
Written by experts from around the globe, this book is essential reading for all clinicians and basic scientists studying the staphylococci.
Chapter
Chapter 3
Evolution and Taxonomy
of Staphylococci
pp.：
33 – 45
Chapter 4
Molecular Basis of Pathogenicity
pp.：
45 – 79
Chapter 5
Adaptation to Stress: Biofilms and
Small-colony Variants
pp.：
79 – 123
Chapter 6
Exotoxins
pp.：
123 – 139
Chapter 7
Host Defense Against Staphylococcal
Infection
pp.：
139 – 161
Antimicrobial Resistance in
Staphylococci
pp.：
161 – 184
Chapter 9
Resistance to Glycopeptides
pp.：
184 – 207
Chapter 8
Resistance to b -Lactam Antibiotics
pp.：
184 – 184
Chapter 10
Resistance to Other Agents
pp.：
207 – 224
Laboratory Studies
pp.：
224 – 249
Section II
Epidemiology of Staphylococcal
Infection
pp.：
249 – 267
Chapter 11
Issues in the Identification and
Susceptibility Testing of Staphylococci
pp.：
249 – 249
Chapter 12
Colonization with Staphylococcus
aureus and the Role of Colonization
in Causing Infection
pp.：
267 – 269
Chapter 13
Epidemiology of Community-associated
Staphylococcus aureus Infections
pp.：
269 – 286
Chapter 14
Epidemiology of Healthcare-associated
Staphylococcus aureus Infections
pp.：
286 – 304
Chapter 15
Epidemiology of Coagulase-negative
Staphylococci and Infections Caused
by these Organisms
pp.：
304 – 324
Section III
Diseases Caused by Staphylococci
pp.：
324 – 347
Chapter 16
Staphylococcus aureus Bacteremia
and Endocarditis
pp.：
347 – 349
Chapter 17
Surgical-site Infections and
Surgical Prophylaxis
pp.：
349 – 360
Chapter 18
Infections of Intravascular Catheters
and Vascular Devices
pp.：
360 – 377
Chapter 19
Skin and Soft Tissue Infections
pp.：
377 – 392
Chapter 20
Central Nervous System Infections
pp.：
392 – 409
Chapter 21
Diseases of the Eye
pp.：
409 – 428
Chapter 22
Osteomyelitis and Other Bone and
Joint Infections
pp.：
428 – 438
Chapter 23
Staphylococcal Pneumonia
pp.：
438 – 458
Chapter 24
Urinary Tract Infections
pp.：
458 – 469
Chapter 25
Toxic Shock Syndrome
pp.：
469 – 484
Chapter 26
Toxin-mediated Syndromes
pp.：
484 – 498
Chapter 27
Staphylococcal Diarrhea and
Enterocolitis
pp.：
498 – 511
Chapter 28
Infections in Immunocompromised
Patients
pp.：
511 – 519
Chapter 29
Clinical Manifestations of Community-acquired
MRSA Infections
pp.：
519 – 535
Section IV
Prevention and Treatment of
Staphylococcal Infections
pp.：
535 – 553
Chapter 30
Elimination of Staphylococcus aureus
Carriage: Importance and Strategies
pp.：
553 – 555
Chapter 31
Treatment of Staphylococcal Infection
pp.：
555 – 584
Chapter 32
Vaccine-based Strategies for Prevention
of Staphylococcus aureus Infection
pp.：
584 – 608
Staphylococci in Human Disease
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