Molecular Analysis and Genome Discovery

Author： Ralph Rapley  

Publisher： John Wiley & Sons Inc‎

Publication year： 2011

E-ISBN: 9781119977445

P-ISBN(Hardback):  9780470758779

Subject： R446 laboratory diagnosis

Language： ENG

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Description

Molecular Analysis and Genome Discovery, Second Edition is a completely revised and updated new edition of this successful book. The text provides a comprehensive overview of recent developments in the fast moving field of molecular based diagnostics of disease markers. Key concepts and applications are provided alongside practical information on current techniques currently being researched and developed. Each chapter offers an up-to-date analysis of the subject encompassing the very latest technology platforms and is an essential reference for researchers in the field looking for an up-to-date overview of the subject. The book will also be an indispensable resource for those working in the biotechnology and pharmaceutical industries. New for this edition: chapters on Genotyping through Mutation Detection; Differential Gene Expression; Haplotyping and Molecular Profiling.

Chapter

Contents

pp.：  1 – 7

Preface

pp.：  7 – 11

Contributors

pp.：  11 – 13

1 Overview of Genotyping

pp.：  13 – 17

2 DNA Chip Analysis in Genome Discovery

pp.：  17 – 40

3 qPCR, Theory, Reliability and Use in Molecular Analysis

pp.：  40 – 59

4 DNA Analysis in Droplet-Based Microfluidic Devices

pp.：  59 – 72

5 High-Resolution Melt Profiling

pp.：  72 – 97

6 Massively Parallel Sequencing

pp.：  97 – 130

7 Aptamers for Analysis: Nucleic Acids Ligands in the Post-Genomic Era

pp.：  130 – 151

8 Use of Nanotechnology for Enhancing of Cancer Biomarker Discovery and Analysis: A Molecular Approach

pp.：  151 – 191

9 Chip-Based Proteomics

pp.：  191 – 209

10 Antibody Microarrays in Proteome Profiling

pp.：  209 – 235

11 Biomarker Detection and Molecular Profiling by Multiplex Microbead Suspension Array Based Immunoproteomics

pp.：  235 – 260

12 Mass Spectrometry in Metabolomics

pp.：  260 – 287

Index

pp.：  287 – 315

LastPages

pp.：  315 – 317

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