Inflammatory Bowel Disease :Translating Basic Science into Clinical Practice

Publication subTitle :Translating Basic Science into Clinical Practice

Author: Stephan R. Targan  

Publisher: John Wiley & Sons Inc‎

Publication year: 2010

E-ISBN: 9781444318425

P-ISBN(Hardback):  9781405157254

Subject: R5 Internal Medicine

Language: ENG

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Description

This is the state-of–the-art book on inflammatory bowel disease you have been waiting for

Written and edited by international experts in gastroenterology this up-to-date volume provides a complete review of the basic science behind inflammatory bowel disease (IBD), as well as evidence-based clinical guidance on diagnosis, treatment and long-term management of IBD.

In 50 chapters the authors cover the latest and most promising treatment modalities and the science behind them. There are chapters which cover the advances in the medical and surgical treatment of conditions such as Crohn's disease and ulcerative colitis, as well as chapters focusing on nutrition, imaging and complementary medicine.

This is an invaluable information resource for all those in the medical team treating patients with IBD. Whether you are a gastroenterologist, gastrointestinal surgeon or GI nurse specialist this book deserves a place in your library.

Chapter

Contents

pp.:  1 – 7

List of Contributors

pp.:  7 – 9

Preface

pp.:  9 – 15

5 In Vivo Models of Inflammatory Bowel Disease

pp.:  32 – 41

6 Factors Affecting Mucosal Homeostasis: a Fine Balance

pp.:  41 – 68

7 Innate Immunity and its Implications on Pathogenesis of Inflammatory Bowel Disease

pp.:  68 – 80

8 Adaptive Immunity: Effector and Inhibitory Cytokine Pathways in Gut Inflammation

pp.:  80 – 98

9 Host Response to Bacterial Homeostasis

pp.:  98 – 108

10 Cytokines and Chemokines in Mucosal Homeostasis

pp.:  108 – 135

11 The Role of the Vasculature in Chronic Intestinal Inflammation

pp.:  135 – 173

12 Biological Basis of Healing and Repair in Remission and Relapse

pp.:  173 – 186

13 The Bidirectional Relationship of Gut Physiological Systems and the Mucosal Immune System

pp.:  186 – 198

14 Extraintestinal Consequences of Mucosal Inflammation

pp.:  198 – 211

15 Ulcerative Colitis and Ulcerative Proctitis: Clinical Course and Complications

pp.:  211 – 228

16 Crohn’s Disease: Clinical Course and Complications

pp.:  228 – 244

17 Practical Inflammatory Bowel Disease Pathology in Patient Management

pp.:  244 – 261

18 The Role of Endoscopy in Diagnosis and Treatment of Inflammatory Bowel Disease

pp.:  261 – 270

19 Imaging in Inflammatory Bowel Disease: Computed Tomography and Magnetic Resonance Enterography, Ultrasound and Enteroscopy

pp.:  270 – 282

20 New Diagnostic Approaches: Integrating Serologics, Endoscopy and Radiology and Genomics

pp.:  282 – 295

21 Considerations in the Differential Diagnosis of Colitis

pp.:  295 – 308

22 Disease Management in Chronic Medical Conditions and its Relevance to Inflammatory Bowel Disease

pp.:  308 – 319

23 Outcomes, Disease Activity Indices and Study Design

pp.:  319 – 339

24 Non-targeted Therapeutics for Inflammatory Bowel Diseases

pp.:  339 – 353

25 Targeted Treatments for Inflammatory Bowel Diseases

pp.:  353 – 376

26 Therapeutic Manipulation of the Microbiota in Inflammatory Bowel Disease: Antibiotics and Probiotics

pp.:  376 – 408

27 The Role of Nutrition in the Evaluation and Treatment of Inflammatory Bowel Disease

pp.:  408 – 418

28 Therapeutic Approaches to the Treatment of Ulcerative Colitis

pp.:  418 – 431

29 Surgical Considerations for Ulcerative Colitis

pp.:  431 – 460

30 Clinical Characteristics and Management of Pouchitis and Ileal Pouch Disorders

pp.:  460 – 477

31 Therapeutic Approaches to the Treatment of Crohn’s Disease

pp.:  477 – 485

32 Surgical Considerations for the Patient with Crohn’s Disease/Perianal Crohn’s Disease

pp.:  485 – 497

33 Diagnostic and Therapeutic Approaches to Postoperative Recurrence in Crohn’s Disease

pp.:  497 – 514

34 Molecular Alterations Associated with Colitis-associated Colon Carcinogenesis

pp.:  514 – 524

35 Cancer Surveillance in Inflammatory Bowel Disease

pp.:  524 – 534

36 Liver Diseases in Patients with Inflammatory Bowel Diseases

pp.:  534 – 544

37 Conditions of the Eyes and Joints Associated with Inflammatory Bowel Disease

pp.:  544 – 569

38 Dermatologic Conditions Associated with Inflammatory Bowel Diseases

pp.:  569 – 578

39 Fertility and Pregnancy in Inflammatory Bowel Diseases

pp.:  578 – 584

40 Inflammatory Bowel Disease in the Pediatric Population

pp.:  584 – 600

41 Lymphocytic and Collagenous Colitis

pp.:  600 – 617

42 Inflammatory Bowel Disease Microcirculation and Diversion, Diverticular and Other Non-infectious Colitides

pp.:  617 – 625

43 Clostridium Difficile-associated Diarrhea

pp.:  625 – 635

44 Colitides of Infectious Origins

pp.:  635 – 659

45 Recent Advances in the Understanding of HIV and Inflammatory Bowel Diseases

pp.:  659 – 674

46 Bone Metabolism and Inflammatory Bowel Disease

pp.:  674 – 681

47 Comprehensive Approach to Patient Risk: Risks Versus Benefits of Immunomodulators and Biologic Therapy for Inflammatory Bowel Disease

pp.:  681 – 694

48 Complementary Medicine

pp.:  694 – 709

49 Legal Pitfalls in Treating Inflammatory Bowel Disease Patients

pp.:  709 – 721

50 The Present and Future of Research and Treatment of Inflammatory Bowel Disease

pp.:  721 – 729

Index

pp.:  729 – 731

Colour plate can be found facing page

pp.:  731 – 757

LastPages

pp.:  757 – 760

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