Boronic Acids :Preparation, Applications in Organic Synthesis and Medicine

Publication subTitle :Preparation, Applications in Organic Synthesis and Medicine

Author: Dennis G. Hall  

Publisher: John Wiley & Sons Inc‎

Publication year: 2006

E-ISBN: 9783527606825

P-ISBN(Hardback):  9783527309917

Subject: O621.3 Organic synthesis chemistry.

Language: ENG

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Description

For the first time, the whole field of organoboronic acids is presented in one comprehensive handbook.
Professor Dennis Hall, a rising star within the community, covers all aspects of this important substance class, including applications in chemistry, biology and medicine.
Starting with an introduction to the structure, properties, and preparation of boronic acid derivatives, together with an overview of their reactions and applications, the book goes on to look at metal-catalyzed borylation of alkanes and arenas, coupling reactions and rhodium-catalyzed additions of boronic acids to alkenes and carbonyl compounds. There follows chapters on copper-promoted C-O and C-N cross-coupling of boronic acids, recent applications in organic synthesis, as well as alpha-haloalkylboronic esters in asymmetric synthesis. Later sections deal with cycloadditions, organoboronic acids, oxazaborolidines as asymmetric inducers, and boronic acid based receptors and sensors. The whole is rounded off with experimental procedures, making this invaluable reading for organic, catalytic and medicinal chemists, as well as those working in organometallics.

Chapter

Table of Contents

pp.:  1 – 7

Preface

pp.:  7 – 17

List of Authors

pp.:  17 – 21

List of Abbreviations

pp.:  21 – 23

3 Coupling Reactions of Areneboronic Acids or Esters with Aromatic Electrophiles

pp.:  129 – 151

4 Rhodium-catalyzed Additions of Boronic Acids to Alkenes and Carbonyl Compounds

pp.:  151 – 199

5 Recent Advances in Copper-promoted C–Heteroatom Bond Cross-coupling Reactions with Boronic Acids and Derivatives

pp.:  199 – 233

6 Recent Advances in the Preparation of Allylboronates and Their Use in Tandem Reactions with Carbonyl Compounds

pp.:  233 – 269

7 Nucleophilic Addition Reactions of Aryl and Alkenylboronic Acids and Their Derivatives to Imines and Iminium Ions

pp.:  269 – 307

8 (α-Haloalkyl)boronic Esters in Asymmetric Synthesis

pp.:  307 – 333

9 Cycloadditions and Other Additions to Alkenyl-, Alkynyl- and Dienyl Boronic Esters

pp.:  333 – 371

10 Organoboronic Acids and Organoborinic Acids as Brønsted–Lewis Acid Catalysts in Organic Synthesis

pp.:  371 – 405

11 Oxazaborolidines as Asymmetric Inducers for the Reduction of Ketones and Ketimines

pp.:  405 – 439

12 Boronic Acid-based Receptors and Sensors for Saccharides

pp.:  439 – 469

13 Biological and Medicinal Applications of Boronic Acids

pp.:  469 – 509

Index

pp.:  509 – 541

LastPages

pp.:  541 – 577

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