Prodrugs and Targeted Delivery
：Towards Better ADME Properties, Volume 47
( Methods and Principles in Medicinal Chemistry )
Publication subTitle ：Towards Better ADME Properties, Volume 47
Publication series ：Methods and Principles in Medicinal Chemistry
Author： Jarkko Rautio
Publisher： John Wiley & Sons Inc
Publication year： 2010
E-ISBN: 9783527633173
P-ISBN(Hardback): 9783527326037
Subject： R914 pharmaceutical chemistry
Language： ENG
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Description
This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs.
Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development.
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