Chapter
10. DISTRIBUTION OF NUCLEIC ACIDS WITHIN EUKARYOTIC CELLS
pp.:
32 – 34
11. TYPES OF RNA MOLECULES
pp.:
34 – 36
12. THE ANATOMY OF EUKARYOTIC CHROMOSOMES
pp.:
36 – 38
13. ORGANISATION OF GENES WITHIN CHROMOSOMES
pp.:
38 – 42
14. THE MOLECULAR ANATOMY OF EUKARYOTIC GENES
pp.:
42 – 46
15. CHROMOSOME ABERRATIONS AND LINKS TO HUMAN DISEASE
pp.:
46 – 48
16. TYPES OF MUTATIONS AND THEIR EFFECTS
pp.:
48 – 50
17. FORMS OF CHEMICALLY ALTERED DNA
pp.:
50 – 52
18. DNA REPAIR MECHANISMS
pp.:
52 – 54
19. LINKAGE ANALYSIS
pp.:
54 – 56
20. PEDIGREE ANALYSIS AND MODES OF INHERITANCE
pp.:
56 – 58
21. GENES DICTATE THE NATURE OF PROTEINS
pp.:
58 – 60
22. THE NATURE OF THE GENETIC CODE
pp.:
60 – 64
23. TRANSCRIPTION: FORMING GENETIC MESSAGES
pp.:
64 – 66
24. POST-TRANSCRIPTIONAL PROCESSING OF MESSENGER RNA
pp.:
66 – 70
25. TRANSFER AND RIBOSOMAL RNA PROCESSING/MODIFICATION
pp.:
70 – 72
26. MECHANISMS REGULATING GENE EXPRESSION
pp.:
72 – 74
27. TRANSCRIPTIONAL REGULATORY SEQUENCES
pp.:
74 – 76
28. OPERONS AND PROKARYOTIC CONTROL OF GENE EXPRESSION
pp.:
76 – 78
29. TRANSCRIPTION FACTORS AND GENE EXPRESSION
pp.:
78 – 80
30. IN VIVO TRANSLATION: DECODING GENETIC MESSAGES
pp.:
80 – 84
31. SEQUENCES INVOLVED IN CELLULAR PROTEIN TARGETING
pp.:
84 – 86
32. EUKARYOTIC CELL DIVISION: MITOSIS AND MEIOSIS
pp.:
86 – 90
33. MOLECULAR MECHANISMS OF CELL CYCLE CONTR0L
pp.:
90 – 92
34. GENETIC RECOMBINATION MECHANISMS
pp.:
92 – 94
35. GENE TRANSFER DURING BACTERIAL REPRODUCTION
pp.:
94 – 96
36. TRANSPOSABLE GENETIC ELEMENTS: TRANSPOSONS
pp.:
96 – 100
37. IN VIVO DNA REPLICATION
pp.:
100 – 104
38. GENETIC CONTROL OF DEVELOPMENT
pp.:
104 – 108
39. THE NATURAL BIOLOGY OF BACTERIOPHAGES
pp.:
108 – 110
40. BACTERIOPHAGE GENETICS
pp.:
110 – 114
41. RECOMBINANT DNA TECHNOLOGY
pp.:
114 – 116
42. ENZYMES COMMONLY USED IN MOLECULAR BIOLOGY METHODS
pp.:
116 – 118
43. RESTRICTION ENDONUCLEASES
pp.:
118 – 120
44. RESTRICTION FRAGMENT LENGTH POLYMORPHISMS
pp.:
120 – 122
45. ISOLATION OF NUCLEIC ACIDS FROM CELLS AND TISSUES
pp.:
122 – 126
46. VISUALISING NUCLEIC ACIDS
pp.:
126 – 128
47. ELECTROPHORESIS OF NUCLEIC ACIDS
pp.:
128 – 130
48. IN VITRO HYBRIDISATION
pp.:
130 – 132
49. TYPES OF HYBRIDISATION ASSAY FORMATS
pp.:
132 – 134
50. SOUTHERN BLOTTING
pp.:
134 – 136
51. IN SITU HYBRIDISATION
pp.:
136 – 138
52. MEASURING TRANSCRIPTIONAL ACTIVITY VIA MESSENGER RNA
pp.:
138 – 140
53. CONVERTING MESSENGER RNA INTO COMPLEMENTARY DNA
pp.:
140 – 142
54. METHODS FOR DETERMINING DNA NUCLEOTIDE SEQUENCES
pp.:
142 – 146
55. THE POLYMERASE CHAIN REACTION
pp.:
146 – 150
56. ALTERNATIVES TO PCR-BASED IN VITRO DNA/RNA AMPLIFICATION
pp.:
150 – 154
57. IN VITRO TRANSLATION METHODS
pp.:
154 – 156
58. TYPES AND METHODS OF GENE PROBE GENERATION
pp.:
156 – 158
59. CHEMICAL SYNTHESIS OF OLIGONUCLEOTIDES
pp.:
158 – 162
60. TYPES AND APPLICATIONS OF NUCLEOTIDE ANALOGUES
pp.:
162 – 164
61. METHODS FOR LABELLING GENE PROBES
pp.:
164 – 168
62. FUNDAMENTAL PRINCIPLES OF CLONING
pp.:
168 – 170
63. THE NATURE OF CLONING VECTORS
pp.:
170 – 172
64. INSERTING FOREIGN DNA INTO VECTORS
pp.:
172 – 174
65. THE DEVELOPMENT OF BACTERIOPHAGE VECTORS
pp.:
174 – 178
66. PLASMIDS: DEVELOPMENT AS CLONING VECTORS
pp.:
178 – 182
67. YEAST-DERIVED PLASMID VECTORS
pp.:
182 – 184
68. PHAGEMIDS, HYBRID PHAGE AND PLASMID CLONING VECTORS
pp.:
184 – 186
69. VECTORS FOR USE IN PLANT AND ANIMAL CELLS
pp.:
186 – 188
70. DELIVERING DNA INTO CELLS
pp.:
188 – 190
71. PRINCIPAL GENOMIC AND cDNA CLONING STRATEGIES
pp.:
190 – 194
72. STRATEGIES FOR IDENTIFYING DESIRABLE RECOMBINANT CLONES
pp.:
194 – 196
73. GENE MAPPING TECHNIQUES
pp.:
196 – 200
74. DETECTING DNA-PROTEIN INTERACTION SITES
pp.:
200 – 204
75. DETECTING PROMOTER AND ENHANCER SEQUENGES
pp.:
204 – 206
76. METHODS FOR IDENTIFYING PROTEIN-ENCODING REGIONS
pp.:
206 – 210
77. GENETIC FINGERPRINTING
pp.:
210 – 212
78. ANALYSING ANCIENT DNA
pp.:
212 – 214
79. IN VITRO MUTAGENESIS METHODS
pp.:
214 – 218
80. GENETICALLY MODIFIED MICRO-ORGANISMS
pp.:
218 – 220
81. GENETICALLY ENGINEERED PLANTS
pp.:
220 – 222
82. GENETICALLY ENGINEERED ANIMALS
pp.:
222 – 224
83. MOLECULAR TECHNIQUES IN PRENATAL DIAGNOSIS
pp.:
224 – 226
84. THE GENETICS OF CYSTIC FIBROSIS
pp.:
226 – 230
85. THE DYSTROPHIN GENE AND MUSCULAR DYSTROPHIES
pp.:
230 – 234
86. IDENTIFYING THE GENE FOR HUNTINGTON'S DISEASE
pp.:
234 – 236
87. LIPOPROTEIN GENES AND CORONARY HEART DISEASE
pp.:
236 – 238
88. THE DETECTION OF MICROBIAL INFECTIONS
pp.:
238 – 240
89. MOLECULAR BIOLOGY OF HUMAN IMMUNODEFICIENCY VIRUS AND AIDS
pp.:
240 – 244
90. ENGINEERING MICROBIAL BIOLUMINESCENCE
pp.:
244 – 246
91. RECOMBINANT DNA METHODS IN VACCINE DEVELOPMENT
pp.:
246 – 248
92. RECEPTORS AND CELLULAR SIGNALLING MECHANISMS
pp.:
248 – 252
93. ONCOGENES AND THE MOLECULAR BASIS OF CANCER
pp.:
252 – 256
94. MOLECULAR DIAGNOSIS AND THERAPY OF CANCERS
pp.:
256 – 258
95. DRUG DEVELOPMENT USING RECOMBINANT DNA APPROACHES
pp.:
258 – 260
96. PROTEIN ENGINEERING
pp.:
260 – 264
97. IMMUNOGLOBULIN GENETICS
pp.:
264 – 268
98. GENETIC ENGINEERING OF RECOMBINANT ANTIBODIES
pp.:
268 – 272
99. CURRENT APPROACHES TO GENE THERAPY
pp.:
272 – 274
100. THE HUMAN GENOME MAPPING PROJECT
pp.:
274 – 278
BIBLIOGRAPHY
pp.:
278 – 323