Early phenotypes that presage late-onset neurodegenerative disease allow testing of modifiers in Hdh CAG knock-in mice

By Borchelt D.R.  

Human Molecular Genetics, Vol. 11, Iss. 6, 2002-03 ,pp. : 633-640

Oxford University Press

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Specific progressive cAMP reduction implicates energy deficit in presymptomatic Huntington's disease knock-in mice

By Persichetti F.   Gines S.   Seong I.S.   Fossale E.   Ivanova E.   Gusella J.F.   Wheeler V.C.   Trettel F.   MacDonald M.E.  

Human Molecular Genetics, Vol. 12, Iss. 5, 2003-03 ,pp. : 497-508

Oxford University Press

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Genetic background modifies nuclear mutant huntingtin accumulation and HD CAG repeat instability in Huntington's disease knock-in mice

By Lloret Alejandro   Dragileva Ella   Teed Allison   Espinola Janice   Fossale Elisa   Gillis Tammy   Lopez Edith   Myers Richard H.   MacDonald Marcy E.   Wheeler Vanessa C.  

Human Molecular Genetics, Vol. 15, Iss. 12, 2006-06 ,pp. : 2015-2024

Oxford University Press

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Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in Hdh Q92 and Hdh Q111 knock-in mice

By Wheeler Vanessa C.  

Human Molecular Genetics, Vol. 9, Iss. 4, 2000-03 ,pp. : 503-513

Oxford University Press

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A Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice

By Iannicola C.  

Human Molecular Genetics, Vol. 8, Iss. 5, 1999-05 ,pp. : 763-774

Oxford University Press

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