Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage

By Shirendeb Ulziibat   Reddy Arubala P.   Manczak Maria   Calkins Marcus J.   Mao Peizhong   Tagle Danilo A.   Hemachandra Reddy P.  

Human Molecular Genetics, Vol. 20, Iss. 7, 2011-04 ,pp. : 1438-1455

Oxford University Press

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Minocycline inhibits cell death and decreases mutant Huntingtin aggregation by targeting Apaf-1

By Sancho Mónica   Herrera Andrés E.   Gortat Anna   Carbajo Rodrigo J.   Pineda-Lucena Antonio   Orzáez Mar   Pérez-Payá Enrique  

Human Molecular Genetics, Vol. 20, Iss. 18, 2011-09 ,pp. : 3545-3553

Oxford University Press

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Mutant huntingtin inhibits clathrin-independent endocytosis and causes accumulation of cholesterol in vitro and in vivo

By Trushina Eugenia   Singh Raman Deep   Cao Sheng   Shah Vijay H.   Parton Robert G.   Pagano Richard E.   McMurray Cynthia T.  

Human Molecular Genetics, Vol. 15, Iss. 24, 2006-12 ,pp. : 3578-3591

Oxford University Press

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Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release

By Choo Yeun Su  

Human Molecular Genetics, Vol. 13, Iss. 14, 2004-07 ,pp. : 1407-1420

Oxford University Press

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Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease

By Shirendeb Ulziibat P.   Calkins Marcus J.   Manczak Maria   Anekonda Vishwanath   Dufour Brett   McBride Jodi L.   Mao Peizhong   Reddy P. Hemachandra  

Human Molecular Genetics, Vol. 21, Iss. 2, 2012-01 ,pp. : 406-420

Oxford University Press

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