Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease

By Shirendeb Ulziibat P.   Calkins Marcus J.   Manczak Maria   Anekonda Vishwanath   Dufour Brett   McBride Jodi L.   Mao Peizhong   Reddy P. Hemachandra  

Human Molecular Genetics, Vol. 21, Iss. 2, 2012-01 ,pp. : 406-420

Oxford University Press

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Mutant huntingtin alters MAPK signaling pathways in PC12 and striatal cells: ERK1/2 protects against mutant huntingtin-associated toxicity

By Apostol Barbara L.   Illes Katalin   Pallos Judit   Bodai Laszlo   Wu Jun   Strand Andrew   Schweitzer Erik S.   Olson James M.   Kazantsev Aleksey   Marsh J. Lawrence  

Human Molecular Genetics, Vol. 15, Iss. 2, 2006-01 ,pp. : 273-285

Oxford University Press

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Protein kinase-A activity in PRKAR1A -mutant cells, and regulation of mitogen-activated protein kinases ERK1/2

By Robinson-White A.  

Human Molecular Genetics, Vol. 12, Iss. 13, 2003-07 ,pp. : 1475-1484

Oxford University Press

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A structure-based analysis of huntingtin mutant polyglutamine aggregation and toxicity: evidence for a compact beta-sheet structure

By Poirier Michelle A.   Jiang Haibing   Ross Christopher A.  

Human Molecular Genetics, Vol. 14, Iss. 6, 2005-03 ,pp. : 765-774

Oxford University Press

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Intersectin enhances huntingtin aggregation and neurodegeneration through activation of c-Jun-NH 2 -terminal kinase

By Scappini Erica   Koh Tong-Wey   Martin Negin P.   O'Bryan John P.  

Human Molecular Genetics, Vol. 16, Iss. 15, 2007-08 ,pp. : 1862-1871

Oxford University Press

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