Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis

By Reis Surya A.   Thompson Morgan N.   Lee Jong-Min   Fossale Elisa   Kim Hyung-Hwan   Liao James K.   Moskowitz Michael A.   Shaw Stanley Y.   Dong Linda   Haggarty Stephen J.   MacDonald Marcy E.   Seong Ihn Sik  

Human Molecular Genetics, Vol. 20, Iss. 12, 2011-06 ,pp. : 2344-2355

Oxford University Press

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Premature death and neurologic abnormalities in transgenic mice expressing a mutant huntingtin exon-2 fragment

By Tebbenkamp Andrew T.N.   Swing Debbie   Tessarollo Lino   Borchelt David R.  

Human Molecular Genetics, Vol. 20, Iss. 8, 2011-04 ,pp. : 1633-1642

Oxford University Press

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Striatal cells from mutant huntingtin knock-in mice are selectively vulnerable to mitochondrial complex II inhibitor-induced cell death through a non-apoptotic pathway

By Ruan Qingmin  

Human Molecular Genetics, Vol. 13, Iss. 7, 2004-04 ,pp. : 669-681

Oxford University Press

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Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed largely of a smaller proteolytic derivative

By Tebbenkamp Andrew T.N.   Green Cameron   Xu Guilian   Denovan-Wright Eileen M.   Rising Aaron C.   Fromholt Susan E.   Brown Hilda H.   Swing Debbie   Mandel Ronald J.   Tessarollo Lino   Borchelt David R.  

Human Molecular Genetics, Vol. 20, Iss. 14, 2011-07 ,pp. : 2770-2782

Oxford University Press

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Preferential accumulation of N-terminal mutant huntingtin in the nuclei of striatal neurons is regulated by phosphorylation

By Havel Lauren S.   Wang Chuan-En   Wade Brandy   Huang Brenda   Li Shihua   Li Xiao-Jiang  

Human Molecular Genetics, Vol. 20, Iss. 7, 2011-04 ,pp. : 1424-1437

Oxford University Press

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