The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

By Gloeckner Christian Johannes   Kinkl Norbert   Schumacher Annette   Braun Ralf J.   O'Neill Eric   Meitinger Thomas   Kolch Walter   Prokisch Holger   Ueffing Marius  

Human Molecular Genetics, Vol. 15, Iss. 2, 2006-01 ,pp. : 223-232

Oxford University Press

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Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity

By West Andrew B.   Moore Darren J.   Choi Catherine   Andrabi Shaida A.   Li Xiaojie   Dikeman Dustin   Biskup Saskia   Zhang Zhenshui   Lim Kah-Leong   Dawson Valina L.   Dawson Ted M.  

Human Molecular Genetics, Vol. 16, Iss. 2, 2007-01 ,pp. : 223-232

Oxford University Press

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C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1

By Sim Chou Hung   Lio Daisy Sio Seng   Mok Su San   Masters Colin L.   Hill Andrew F.   Culvenor Janetta G.   Cheng Heung-Chin  

Human Molecular Genetics, Vol. 15, Iss. 21, 2006-11 ,pp. : 3251-3262

Oxford University Press

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A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2

By Roessler Erich  

Human Molecular Genetics, Vol. 14, Iss. 15, 2005-08 ,pp. : 2181-2188

Oxford University Press

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LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model

By Alegre-Abarrategui Javier   Christian Helen   Lufino Michele M.P.   Mutihac Ruxandra   Venda Lara Loureno   Ansorge Olaf   Wade-Martins Richard  

Human Molecular Genetics, Vol. 18, Iss. 21, 2009-11 ,pp. : 4022-4034

Oxford University Press

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