

Author: Tas Faruk Duranyildiz Derya Oguz Hilal Camlica Hakan Yasasever Vildan Topuz Erkan
Publisher: Humana Press, Inc
ISSN: 1357-0560
Source: Medical Oncology, Vol.25, Iss.4, 2008-12, pp. : 431-436
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
Vascular endothelial growth factor (VEGF) is a critical regulator of angiogenesis that stimulates proliferation, migration, and metastasis of melanoma. In literature, all studies concerning influences of matrix metalloproteinases (MMPs) and antiapoptotic proteins on VEGF-induced angiogenesis in melanoma patients have been performed in tissue scale in melanoma. The objective of this study was to determine the value of circulating serum VEGF and its possible mechanisms of angiogenesis by circulating VEGF, MMP-3, and Bcl-2 in patients with melanoma. Fifty-one patients with cutaneous melanoma pathologically verified at different stages, and eighteen healthy controls were investigated. Serum VEGF, MMP-3, and Bcl-2 levels were quantitatively analyzed by ELISA. The serum VEGF (
Related content


International Journal of Oncology, Vol. 43, Iss. 3, 2013-01 ,pp. :


By Tas Faruk Duranyildiz Derya Oguz Hilal Camlica Hakan Yasasever Vildan Topuz Erkan
Cancer Investigation, Vol. 24, Iss. 6, 2006-09 ,pp. :


By Potti Anil Moazzam Nauman Langness Eric Sholes Kaley Tendulkar Ketki Koch Michael Kargas Steve
Journal of Cancer Research and Clinical Oncology, Vol. 130, Iss. 2, 2004-02 ,pp. :

