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One‐Pot Synthesis of 2‐Acylimino‐3‐aryl‐thiazoline Derivatives in Aqueous Media

Author: Wang Xicun   Wang Fang   Quan Zhengjun   Zhang Zhang   Wang Mangang  

Publisher: Taylor & Francis Ltd

ISSN: 0039-7911

Source: Synthetic Communications, Vol.36, Iss.17, 2006-08, pp. : 2453-2460

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Abstract

A one‐pot, two‐step synthesis for acyliminothiazolines by treated N,N′‐substituted thioureas with &agr;‐bromocarbonyl compounds under aqueous media was described. Compared to the classical reaction in organic solvents, this method consistently has the advantage of short reaction times, convenient procedures, and mild reaction conditions.

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