B2O3/Al2O3 as an Efficient and Recyclable Catalyst for the Synthesis of β-Amino Alcohols under Solvent-Free Conditions

Author: Zhang Changfu   Chen Jiuxi   Yu Xiaochun   Chen Xian   Wu Huayue   Yu Jianping  

Publisher: Taylor & Francis Ltd

ISSN: 0039-7911

Source: Synthetic Communications, Vol.38, Iss.12, 2008-01, pp. : 1875-1887

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Abstract

A convenient and efficient procedure for the solvent-free synthesis of β-amino alcohols has been achieved via B2O3/Al2O3-promoted highly regioselective ring opening of epoxides with aromatic amines in good to excellent yields at room temperature. Additionally, the catalyst can be recycled without affecting the catalytic property.

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