Regioselective Iodination of Arenes Using Iodine/NaBO3 · 4H2O System in Ionic Liquid

Author: Bhilare Sachin   Deorukhkar Amol   Darvatkar Nitin   Salunkhe Manikrao  

Publisher: Taylor & Francis Ltd

ISSN: 0039-7911

Source: Synthetic Communications, Vol.38, Iss.17, 2008-01, pp. : 2881-2888

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Abstract

A mild, efficient, and simple protocol was developed for iodination of arenes and heterocyclic compounds with molecular iodine catalyzed by sodium perborate in ionic liquid. The methodology offered iodoarenes in good to excellent yields at room temperature. The protocol proved to be highly selective, as a single isomer was formed exclusively in most of the substrates.

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