Simple and Efficient One-Pot, Three-Component, Solvent-Free Synthesis of β-Enaminones via Sonogashira Coupling-Michael Addition Sequences

Author: Palimkar Sanjay   More Vijaykumar   Srinivasan Kumar  

Publisher: Taylor & Francis Ltd

ISSN: 0039-7911

Source: Synthetic Communications, Vol.38, Iss.9, 2008-01, pp. : 1456-1469

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Abstract

A simple, efficient, and environmentally friendly one-pot, three-component synthesis of β-enaminones via Sonogashira coupling-Michael addition sequences under solvent-free conditions has been reported. Also the synthesis of β-enaminones has been achieved in high yields by the direct reaction of amines with ynones under solvent-free conditions.

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