Sites of Interaction of Streptogramin A and B Antibiotics in the Peptidyl Transferase Loop of 23 S rRNA and the Synergism of their Inhibitory Mechanisms

By Porse B.T.   Garrett R.A.  

Journal of Molecular Biology, Vol. 286, Iss. 2, 1999-02 ,pp. : 375-387

Academic Press

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Mutations in the Peptidyl Transferase Center of 23 S rRNA Reveal the Site of Action of Sparsomycin, a Universal Inhibitor of Translation

By Tan G.T.   deBlasio A.   Mankin A.S.  

Journal of Molecular Biology, Vol. 261, Iss. 2, 1996-08 ,pp. : 222-230

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Resistance Mutations in 23 S rRNA Identify the Site of Action of the Protein Synthesis Inhibitor Linezolid in the Ribosomal Peptidyl Transferase Center

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Mutations at Nucleotides G2251 and U2585 of 23 S rRNA Perturb the Peptidyl Transferase Center of the Ribosome

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Journal of Molecular Biology, Vol. 266, Iss. 1, 1997-02 ,pp. : 40-50

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A Sparsomycin-resistant Mutant of Halobacterium salinarium Lacks a Modification at Nucleotide U2603 in the Peptidyl Transferase Centre of 23 S rRNA

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