Human Glutathione Transferase A4-4 Crystal Structures and Mutagenesis Reveal the Basis of High Catalytic Efficiency with Toxic Lipid Peroxidation Products

Author： Bruns C.M.   Hubatsch I.   Ridderström M.   Mannervik B.   Tainer J.A.  

Publisher： Academic Press

ISSN： 0022-2836

Source： Journal of Molecular Biology, Vol.288, Iss.3, 1999-05, pp. : 427-439

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Related content

Cellular Response to the Redox Active Lipid Peroxidation Products: Induction of Glutathione S-Transferase P by 4-Hydroxy-2-nonenal

By Fukuda A.   Nakamura Y.   Ohigashi H.   Osawa T.   Uchida K.  

Biochemical and Biophysical Research Communications, Vol. 236, Iss. 2, 1997-07 ,pp. : 505-509

Elsevier

Access to resources Recommend Favorite

Differential Catalytic Efficiency of Allelic Variants of Human Glutathione S-Transferase Pi in Catalyzing the Glutathione Conjugation of Thiotepa

By Srivastava S.K.   Singhal S.S.   Hu X.   Awasthi Y.C.   Zimniak P.   Singh S.V.  

Archives of Biochemistry and Biophysics, Vol. 366, Iss. 1, 1999-06 ,pp. : 89-94

Elsevier

Access to resources Recommend Favorite

A Highly Acidic Tyrosine 9 and a Normally Titrating Tyrosine 212 Contribute to the Catalytic Mechanism of Human Glutathione Transferase A4-4

By Hubatsch I.   Mannervik B.  

Biochemical and Biophysical Research Communications, Vol. 280, Iss. 3, 2001-01 ,pp. : 878-882

Elsevier

Access to resources Recommend Favorite

Mechanism of Differential Catalytic Efficiency of Two Polymorphic Forms of Human Glutathione S-Transferase P1-1 in the Glutathione Conjugation of Carcinogenic Diol Epoxide of Chrysene

By Hu X.   Ji X.   Srivastava S.K.   Xia H.   Awasthi S.   Nanduri B.   Awasthi Y.C.   Zimniak P.   Singh S.V.  

Archives of Biochemistry and Biophysics, Vol. 345, Iss. 1, 1997-09 ,pp. : 32-38

Elsevier

Access to resources Recommend Favorite

Lipid peroxidation products in human subretinal fluid

By Bosch-Morell F.   Sanz A.   Diaz-Llopis M.   Romero F.J.  

Free Radical Biology and Medicine, Vol. 20, Iss. 7, 1996-01 ,pp. : 899-903

Elsevier

Access to resources Recommend Favorite