Refined Model for Primer/Template Binding by HIV-1 Reverse Transcriptase: Pre-steady-state Kinetic Analyses of Primer/Template Binding and Nucleotide Incorporation Events Distinguish Between Different Binding Modes Depending on the Nature of the Nucleic Acid Substrate

Author： Wöhrl B.M.   Krebs R.   Goody R.S.   Restle T.  

Publisher： Academic Press

ISSN： 0022-2836

Source： Journal of Molecular Biology, Vol.292, Iss.2, 1999-09, pp. : 333-344

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Related content

Crystal Structures of an N-terminal Fragment from Moloney Murine Leukemia Virus Reverse Transcriptase Complexed with Nucleic Acid: Functional Implications for Template-primer Binding to the Fingers Domain

By Najmudin S.   Coté M.L.   Sun D.   Yohannan S.   Montano S.P.   Gu J.   Georgiadis M.M.  

Journal of Molecular Biology, Vol. 296, Iss. 2, 2000-02 ,pp. : 613-632

Academic Press

Access to resources Recommend Favorite

Human replication protein A (RPA) binds a primer–template junction in the absence of its major ssDNA‐binding domains

By Pestryakov Pavel E.   Khlimankov Denis Y.   Bochkareva Elena   Bochkarev Alexey   Lavrik Olga I.  

Nucleic Acids Research, Vol. 32, Iss. 6, 2004-03 ,pp. : 1894-1903

Oxford University Press

Access to resources Recommend Favorite

Novel mutations in Moloney Murine Leukemia Virus reverse transcriptase increase thermostability through tighter binding to template-primer

By Arezi Bahram   Hogrefe Holly  

Nucleic Acids Research, Vol. 37, Iss. 2, 2009-02 ,pp. : 473-481

Oxford University Press

Access to resources Recommend Favorite

The Effects of Internal Primer-Template Mismatches on RT-PCR: HIV-1 Model Studies

By Christopherson Cindy   Sninsky John   Kwok Shirley  

Nucleic Acids Research, Vol. 25, Iss. 3, 1997-01 ,pp. : 654-658

Oxford University Press

Access to resources Recommend Favorite

Selection of primer-template sequences that bind human immunodeficiency virus reverse transcriptase with high affinity

By DeStefano Jeffrey J.   Cristofaro Jason V.  

Nucleic Acids Research, Vol. 34, Iss. 1, 2006-01 ,pp. : 130-139

Oxford University Press

Access to resources Recommend Favorite