A pH-dependent Conformational Change, Rather than the Chemical Step, Appears to be Rate-limiting in the Hammerhead Ribozyme Cleavage Reaction

Author: Murray J.B.   Dunham C.M.   Scott W.G.  

Publisher: Academic Press

ISSN: 0022-2836

Source: Journal of Molecular Biology, Vol.315, Iss.2, 2002-01, pp. : 121-130

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Abstract