A Stochastic Model of Cell Replicative Senescence Based on Telomere Shortening, Oxidative Stress, and Somatic Mutations in Nuclear and Mitochondrial DNA

Author: Sozou P.D.   Kirkwood T.B.L.  

Publisher: Academic Press

ISSN: 0022-5193

Source: Journal of Theoretical Biology, Vol.213, Iss.4, 2001-12, pp. : 573-586

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Abstract