FAD Mutations in Presenilin-1 or Amyloid Precursor Protein Decrease the Efficacy of a γ-Secretase Inhibitor: Evidence for Direct Involvement of PS1 in the γ-Secretase Cleavage Complex

Author： Xia W.   Ostaszewski B.L.   Kimberly W.T.   Rahmati T.   Moore C.L.   Wolfe M.S.   Selkoe D.J.  

Publisher： Academic Press

ISSN： 0969-9961

Source： Neurobiology of Disease, Vol.7, Iss.6, 2000-12, pp. : 673-681

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