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Author: Brenz Verca M.S. Widmer D.A.J. Wagner G.C. Dreyer J-L.
Publisher: Academic Press
ISSN: 1044-7431
Source: Molecular and Cellular Neuroscience, Vol.17, Iss.2, 2001-02, pp. : 303-316
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Abstract
CD81, a tetraspanin transmembrane protein involved in cell adhesion, was found by differential display to be upregulated in the nucleus accumbens of rat brain following acute cocaine treatment (four injections of 30 mg/kg every 2 h followed by 24 h withdrawal). Cocaine-induced expression of CD81 in adult rat brain was confirmed by quantitative real-time RT-PCR. Its expression in neurons and its function in the brain are unknown.
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