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Human apolipoprotein(a) kringle V inhibits angiogenesis in vitro and in vivo by interfering with the activation of focal adhesion kinases

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Volume 13, Number 2 (1998), in Article No. PT980898, “Bacterial Expression and Characterization of Human Recombinant Apolipoprotein(a) Kringle IV Type 9,” by Fu-Zon Chung, Lan-Hsin Wu, Helen T. Lee, William T. Mueller, Mark A. Spahr, Scott R. Eaton, Ye Tian, Philip D. Settimi, Dale L. Oxender, and Randy Ramharack, pages 222–228:

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Immunoglobulin Fc domain fusion to apolipoprotein(a) kringle V significantly prolongs plasma half-life without affecting its anti-angiogenic activity

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