PXR and CAR: Nuclear Receptors which Play a Pivotal Role in Drug Disposition and Chemical Toxicity

Author： Stanley Lesley Horsburgh Brian Ross Jillian Scheer Nico Roland Wolf C.

ISSN： 0360-2532

Source： Drug Metabolism Reviews, Vol.38, Iss.3, 2006-06, pp. : 515-597

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Related content

Nuclear receptors PXR and CAR: implications for drug metabolism regulation, pharmacogenomics and beyond

By Chai Xiaojuan Zeng Su Xie Wen

Expert Opinion on Drug Metabolism and Toxicology, Vol. 9, Iss. 3, 2013-03 ,pp. : 253-266

Informa Healthcare

Access to resources Recommend Favorite

Nuclear Receptors CAR and PXR in Metabolism and Elimination of Drugs

Current Pharmacogenomics, Vol. 1, Iss. 2, 2003-06 ,pp. : 75-85

Bentham Science Publishers

Access to resources Recommend Favorite

Pharmacogenetic effects of regulatory nuclear receptors (PXR, CAR, RXRα and HNF4α) on docetaxel disposition in Chinese nasopharyngeal cancer patients

By Chew Sin-Chi Lim Joanne Singh Onkar Chen Xiangai Tan Eng-Huat Lee Edmund-JD Chowbay Balram

European Journal of Clinical Pharmacology, Vol. 70, Iss. 2, 2014-02 ,pp. : 155-166

Springer Publishing Company

Access to resources Recommend Favorite

Ligand Recognition by Drug-Activated Nuclear Receptors PXR and CAR: Structural, Site-Directed Mutagenesis and Molecular Modeling Studies

Mini Reviews in Medicinal Chemistry, Vol. 6, Iss. 8, 2006-08 ,pp. : 937-943

Bentham Science Publishers

Access to resources Recommend Favorite

Xenobiotic-Sensing Nuclear Receptors CAR and PXR as Drug Targets in Cholestatic Liver Disease

Current Drug Targets, Vol. 10, Iss. 11, 2009-11 ,pp. : 1156-1163

Bentham Science Publishers

Access to resources Recommend Favorite