The Association Between Maternal Obesity, Glucose Intolerance and Hypertensive Disorders of Pregnancy in Nondiabetic Pregnant Women

Author: Erez-Weiss Idit   Erez Offer   Shoham-Vardi Ilana   Holcberg Gershon   Mazor Moshe  

Publisher: Informa Healthcare

ISSN: 1064-1955

Source: Hypertension in Pregnancy, Vol.24, Iss.2, 2005-04, pp. : 125-136

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Abstract

Objective. The aim of this study is to evaluate whether pregnancy-induced hypertension (PIH) among nondiabetic patients is associated with glucose intolerance. Materials and Methods. A retrospective case-control study was designed including a study group who had pregnancy-induced hypertension or preeclampsia. Patients with normal pregnancy were used as a control group matched to cases by parity. Diabetic patients, nonsingleton pregnancies, and women without prenatal care were excluded. Data concerning fasting glucose levels, glucose challenge test (GCT), and oral glucose tolerance test (OGTT) were collected from patients' files. Results. There were 131 patients in each study group. The study group had significantly higher mean maternal age, mean GCT levels, and mean pregestational body mass index (BMI) (28.0 ± 5.8 vs. 26.5 ± 5.3, p = 0.02; 5.8 ± 1.4 vs. 5.1 ± 1.1 p = 0.0018; 26 ± 5.1 vs. 23 ± 4.0 p

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