Homology modelling of human CYP1A2 based on the CYP2C5 crystallographic template structure

By Lewis D. F. V.   Lake B. G.   Dickins M.   Ueng Y.- F.   Goldfarb P. S.  

Xenobiotica, Vol. 33, Iss. 3, 2003-03 ,pp. : 239-254

Informa Healthcare

Access to resources Recommend Favorite

Molecular modelling of CYP2B6, the human CYP2B isoform, by homology with the substrate-bound CYP102 crystal structure: evaluation of CYP2B6 substrate characteristics, the cytochrome b5 binding site and comparisons with CYP2B1 and CYP2B4

By Lewis D. F. V.   Lake B. G.   P. M. Dickins   Eddershaw J.   Tarbit M. H.   Goldfarb P. S.  

Xenobiotica, Vol. 29, Iss. 4, 1999-04 ,pp. : 361-393

Informa Healthcare

Access to resources Recommend Favorite

Quantitative structure-activity relationships within a homologous series of 7-alkoxyresorufins exhibiting activity towards CYP1A and CYP2B enzymes: molecular modelling studies on key members of the resorufin series with CYP2C5-derived models of human CYP1A1, CYP1A2, CYP2B6 and CYP3A4

By Lewis David F. V.   Lake Brian G.   Dickins M.  

Xenobiotica, Vol. 34, Iss. 6, 2004-06 ,pp. : 501-513

Informa Healthcare

Access to resources Recommend Favorite

Homology modelling of CYP3A4 from the CYP2C5 crystallographic template: analysis of typical CYP3A4 substrate interactions

By Lewis D. F. V.   Lake B. G.   Dickins M.   Goldfarb P. S.  

Xenobiotica, Vol. 34, Iss. 6, 2004-06 ,pp. : 549-569

Informa Healthcare

Access to resources Recommend Favorite

Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site-directed mutagenesis experiments in the CYP2C subfamily

By Lewis D. F. V.   Dickins M.   Weaver R. J.   Eddershaw P. J.   Goldfarb P. S.   Tarbit M. H.  

Xenobiotica, Vol. 28, Iss. 3, 1998-03 ,pp. : 235-268

Informa Healthcare

Access to resources Recommend Favorite