Prediction of differences in in vivo oral clearance of N , N -dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100) between extensive and poor metabolizers from in vitro metabolic data in human liver microsomes lacking CYP2D6 activity and recombinant CYPs

Author： Yamamoto T.   Hagima N.   Nakamura M.   Kohno Y.   Nagata K.   Yamazoe Y.  

Publisher： Informa Healthcare

ISSN： 1366-5928

Source： Xenobiotica, Vol.34, Iss.7, 2004-07, pp. : 687-703

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