Validation of membrane vesicle-based breast cancer resistance protein and multidrug resistance protein 2 assays to assess drug transport and the potential for drug––drug interaction to support regulatory submissions

By Elsby Robert   Smith Veronica   Fox Lisa   Stresser David   Butters Caroline   Sharma Pradeep   Surry Dominic D.  

Xenobiotica, Vol. 41, Iss. 9, 2011-09 ,pp. : 764-783

Informa Healthcare

Access to resources Recommend Favorite

Evaluation of cytochrome P450-mediated drug–drug interactions based on the strategies recommended by regulatory authorities

By Kosugi Yohei   Hirabayashi Hideki   Igari Tomoko   Fujioka Yasushi   Hara Yoko   Okuda Teruaki   Moriwaki Toshiya  

Xenobiotica, Vol. 42, Iss. 2, 2012-02 ,pp. : 127-138

Informa Healthcare

Access to resources Recommend Favorite

Mechanism-based inactivation of human cytochrome P450 enzymes: strategies for diagnosis and drug–drug interaction risk assessment

By Venkatakrishnan K.   Obach R. S.   Rostami-Hodjegan A.  

Xenobiotica, Vol. 37, Iss. 10-11, 2007-11 ,pp. : 1225-1256

Informa Healthcare

Access to resources Recommend Favorite

Interaction of HIV protease inhibitors with OATP1B1, 1B3, and 2B1

By Annaert P.   Ye Z.W.   Stieger B.   Augustijns P.  

Xenobiotica, Vol. 40, Iss. 3, 2010-03 ,pp. : 163-176

Informa Healthcare

Access to resources Recommend Favorite

Transport of Phosphatidylcholine in MDR3-Negative Epithelial Cell Lines via Drug-Induced MDR1 P-Glycoprotein

By Abulrob A-n.G.   Gumbleton M.  

Biochemical and Biophysical Research Communications, Vol. 262, Iss. 1, 1999-08 ,pp. : 121-126

Elsevier

Access to resources Recommend Favorite