Flavin monooxygenases, FMO1 and FMO3, not cytochrome P450 isoenzymes, contribute to metabolism of anti-tumour triazoloacridinone, C-1305, in liver microsomes and HepG2 cells

Author： Fedejko-Kap Barbara   Niemira Magdalena   Radominska-Pandya Anna   Mazerska Zofia  

Publisher： Informa Healthcare

ISSN： 1366-5928

Source： Xenobiotica, Vol.41, Iss.12, 2011-12, pp. : 1044-1055

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Related content

Induction of Cytochrome P-450 1A1 by Omeprazole in Human HepG2 Cells Is Protein Tyrosine Kinase-Dependent and Is Not Inhibited by -Naphthoflavone

By Kikuchi H.   Hossain A.   Yoshida H.   Kobayashi S.  

Archives of Biochemistry and Biophysics, Vol. 358, Iss. 2, 1998-10 ,pp. : 351-358

Elsevier

Access to resources Recommend Favorite

Induction of cytochrome P4501A1 by autoclavable culture medium change in HepG2 cells

By Feng Q.   Kumagai T.   Nakamura Y.   Uchida K.   Osawa T.  

Xenobiotica, Vol. 32, Iss. 11, 2002-11 ,pp. : 1033-1043

Informa Healthcare

Access to resources Recommend Favorite

Deactivation of anti-cancer drug letrozole to a carbinol metabolite by polymorphic cytochrome P450 2A6 in human liver microsomes

By Murai K.   Yamazaki H.   Nakagawa K.   Kawai R.   Kamataki T.  

Xenobiotica, Vol. 39, Iss. 11, 2009-11 ,pp. : 795-802

Informa Healthcare

Access to resources Recommend Favorite

Characterization of Cytochrome P4502E1 Turnover in Transfected HepG2 Cells Expressing Human CYP2E1

By Yang M.X.   Cederbaum A.I.  

Archives of Biochemistry and Biophysics, Vol. 341, Iss. 1, 1997-05 ,pp. : 25-33

Elsevier

Access to resources Recommend Favorite

Metabolism of CJ-036878, N-(3-phenethoxybenzyl)-4-hydroxybenzamide, in liver microsomes and recombinant cytochrome P450 enzymes: metabolite identification by LC-UV/MSn and 1H-NMR

By Nishida H.   Hirai H.   Emoto C.   Iwasaki K.  

Xenobiotica, Vol. 37, Iss. 12, 2007-12 ,pp. : 1394-1407

Informa Healthcare

Access to resources Recommend Favorite