Case studies addressing human pharmacokinetic uncertainty using a combination of pharmacokinetic simulation and alternative first in human paradigms

Author： Harrison Anthony   Gardner Iain   Hay Tanya   Dickins Maurice   Beaumont Kevin   Phipps Alex   Purkins Lynn   Allan Gill   Christian Rachelle   Duckworth Jonathan   Gurrell Ian   Kempshall Sarah   Savage Mark   Seymour Mark   Simpson Marie   Taylor Louise   Turnpenny Paul  

Publisher： Informa Healthcare

ISSN： 1366-5928

Source： Xenobiotica, Vol.42, Iss.1, 2012-01, pp. : 57-74

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