Free Flavonoids from Rhus retinorrhoea Steud, ex Olive

Author: Mossa J S   Sattar Essam Abdel   Abou-Shoer M   Galal A M  

Publisher: Informa Healthcare

ISSN: 1388-0209

Source: Pharmaceutical Biology (Formerly International Journal of Pharmacognosy), Vol.34, Iss.3, 1996-07, pp. : 198-201

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Abstract

The isolation of persicogenin [1], velutin [2] and (2S) 5,3',4' trihydroxy-7-methoxyflavanone [3] and homoeriodictyol [4] from Rhus retinorrhoea (Anacardiaceae) is reported. The antimicrobial activity of the isolated compounds was studied. [1] and [2] were found devoid of any antimicrobial activity while [3] and [4] had weak activity (MIC; 200 μg/ml against Streptococcus faecalis and 300 μg/ml against Staphylococcus aureus . Furthermore, the LC 50 of the pure compounds were determined using the brine shrimp lethality assay, only velutin was significantly active.