Anti-inflammatory and anti-nociceptive effects of Pterodon emarginatus stem bark alcohol extract

Author: de Moraes Weuller   de Matos Lecia   Mariano Nascimento Marcus Vinicius   Realino de Paula Jose   Bara Maria Teresa   Carlos da Cunha Luiz   Valadares Marize   Alves Costa Elson  

Publisher: Informa Healthcare

ISSN: 1388-0209

Source: Pharmaceutical Biology (Formerly International Journal of Pharmacognosy), Vol.47, Iss.2, 2009-02, pp. : 146-150

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Abstract

The tail flick, the acetic acid writhing, the croton oil-induced mouse ear edema, and carrageenan-induced peritonitis tests were used to study the anti-inflammatory effects of the alcohol extract from Pterodon emarginatus Vogel. (Leguminosae/Fabaceae) stem bark. The alcohol extract caused inhibition of acetic acid-induced abdominal writhing, reducing the number of leukocytes (x 107) per mL of peritoneal wash and ear edema formation. The results suggest that Pterodon emarginatus stem bark contains compounds with analgesic and anti-inflammatory actions.

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