Author： Brown D.C. Kelnar C.J.H. Wu F.C.W.
Publisher： Informa Healthcare
ISSN： 1464-5033
Source： Annals of Human Biology, Vol.23, Iss.4, 1996-08, pp. : 273-279
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Abstract
In order to identify metabolic cues involved in the control of onset of male human puberty, 70 pre- and peri-pubertal boys, aged 9·21 ± 0·03 years at the start of the study, had their lean body mass (LBM), basal metabolic rate (BMR) and total daily energy expenditure (TDEE) measured at 6-monthly intervals on three occasions each. Hormonal pubertal activity was assessed by measuring early morning salivary testosterone (ST) at each assessment. A subgroup of 44 boys, who first showed an increase in ST at their third assessment, was identified. In the general population at this stage of development, and in the overall 70 boys studied here, BMR/LBM decreases significantly with age (from 0·185 ± 0·001 to 0·180 ± 0·001 MJ/day per kg over 6 months, p
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