Isotretinoin in dermatology

Author： Amichai B   Grunwald M H  

Publisher： Informa Healthcare

ISSN： 1471-1753

Source： Journal of Dermatological Treatment, Vol.11, Iss.4, 2000-12, pp. : 219-240

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

BACKGROUND: Isotretinoin (13-cis retinoic acid) revolutionized the treatment of acne. Since the early 1980s patients suffering from severe forms of acne have been treated effectively, with less residual cosmetic or psychological damage. OBJECTIVE: The aim of this article is to provide a wide review of isotretinoin, including its clinical applications in dermatology, side effects and drug interactions. DISCUSSION: Isotretinoin affects epidermal cell growth and differentiation as well as sebaceous gland activity, and exhibits immunomodulatory and antiinflammatory properties, which are important in the treatment of a wide range of other cutaneous diseases - mainly disorders of keratinization and also in proliferative diseases. (J Dermatol Treat (2000) 11: 219-240)

Related content

Isotretinoin in Denmark – 20 years on

By Wildfang IL   Nielsen NH   Jemec GBE   Ibsen HHW   Avnstorp C  

Journal of Dermatological Treatment, Vol. 13, Iss. 3, 2002-09 ,pp. : 151-152 (2)

Informa Healthcare

Access to resources Recommend Favorite

Isotretinoin-induced encephalopathy

By Wong Adrian   Williams Matthew   Gibb William  

Journal of Dermatological Treatment, Vol. 21, Iss. 6, 2010-11 ,pp. : 361-362 (2)

Informa Healthcare

Access to resources Recommend Favorite

Misnomers in Dermatology

By Barankin Benjamin   Freiman Anatoli  

Journal of Cutaneous Medicine and Surgery, Vol. 9, Iss. 6, 2005-12 ,pp. : 284-288 (5)

Springer Publishing Company

Access to resources Recommend Favorite

Changing paradigms in dermatology: antivirals in dermatology

By Lin P.   Torres G.   Tyring S.K.  

Clinics in Dermatology, Vol. 21, Iss. 5, 2003-09 ,pp. : 426-446 (21)

Elsevier

Access to resources Recommend Favorite

Follicular mucinosis responding to isotretinoin treatment

By Arca E   Köse O   Taştan HB   Gür AR   Safalı M  

Journal of Dermatological Treatment, Vol. 15, Iss. 6, 2004-12 ,pp. : 391-395 (5)

Informa Healthcare

Access to resources Recommend Favorite