Interferon alpha for the treatment of advanced renal cancer

Author: Ravaud Alain   Dilhuydy Marie-Sarah  

Publisher: Informa Healthcare

ISSN: 1471-2598

Source: Expert Opinion on Biological Therapy, Vol.5, Iss.6, 2005-06, pp. : 749-762

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Abstract

This paper is an overview on the place of IFN-α in metastatic renal cell carcinoma (MRCC). After a presentation of MRCC and the mode of action of IFN-α, the results of studies including IFN-α alone or in combination with IL-2, chemotherapy and other biological modifiers are presented. Finally, new trends for new drugs, including antiangiogenic therapies, are discussed.