Enzyme inhibition activities of teucrium royleanum

Author: Ahmad Bashir   Shah S. M. Mukarram   Khan Haroon   Shah S. M. Hassan  

Publisher: Informa Healthcare

ISSN: 1475-6366

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol.22, Iss.6, 2007-12, pp. : 730-732

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Abstract

The crude methanolic extract and chloroform, ethyl acetate and n-butanol fractions of Teucrium royleanum were examined as inhibitors of actylcholinesterase, butyrylcholinesterase, lipoxygenase and urease. A significant enzyme inhibition activity (52-83%) was shown by the crude methanolic extract and its fractions against acetylcholinesterase, while low to outstanding enzyme inhibitory activity was shown (19-93%) against butyrylcholinesterase. The crude methanolic extract and its various fractions demonstrated low activity against lipoxygenase and inactive against urease.

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