Author: Radovanovic Jelena Todorovic Vera Boricic Ivan Jankovic-Hladni Miroslava Korac Aleksandra
Publisher: Informa Healthcare
ISSN: 1521-0758
Source: Ultrastructural Pathology, Vol.23, Iss.1, 1999-01, pp. : 19-24
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Abstract
The present comparative conventional electron microscopic studies of the liver biopsy in 20 AIDS patients revealed numerous disintegrated mitochondria in hepatocytes, Kupffer cells lymphocytes, and eosinophile leukocytes. It was observed that (1) AIDS mitochondria are clustered, disorganized, and with protruberances; (2) the number of cristae is reduced and they are branched dichotomously; (3) vacuoles are located both within the mitochondria and, in their vicinity, (4) "minimitochondria" are within the ordinary mitochondria; (5) virus-like particles are at the periphery of electron-dense mitochondrial remains.
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