Vitamin D :Molecular, Cellular and Clinical Endocrinology. Proceedings of the Seventh Workshop on Vitamin D, Rancho Mirage, California, USA, April 1988

Publication subTitle :Molecular, Cellular and Clinical Endocrinology. Proceedings of the Seventh Workshop on Vitamin D, Rancho Mirage, California, USA, April 1988

Author: A. W. Norman   K. Schaefer   H. G. Grigoleit   D. von Herrath  

Publisher: De Gruyter‎

Publication year: 1988

E-ISBN: 9783110846713

P-ISBN(Paperback): 9783110114775

Subject:

Language: ENG

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Chapter

Vitamin D Analogues: Potential Inhibitors of Vitamin D Metabolism

pp.:  52 – 62

Synthesis of 26,27-Hexadeutero and Epimeric 26-Trideutero 1,25-Dihydroxycholecalciferols

pp.:  62 – 65

Chemical Synthesis of Vitamin D Analogs with Selective Biological Activities

pp.:  65 – 74

Chemistry of Vitamin D, its Metabolites and Analogs

pp.:  74 – 83

A Practical Synthesis of 1-Alpha-OH Vitamin D3 Analogs

pp.:  83 – 91

Synthesis of Biologically Active Cyclopropane Analogues of 1α, 25-Dihydroxy- and 1α-Hydroxy-Vitamin D3

pp.:  91 – 93

Asymmetric Synthesis of 1α, 25-Dihydroxyvitamin D3 and Analogs

pp.:  93 – 94

Chemical Synthesis and Studies of 9(11)-Dehydrovitamin D and its 11-Substituted Analogues

pp.:  94 – 98

A- and C-Ring Modified Vitamin D Analogues: A Mechanistic Study of the [1,7]-Sigmatropic Hydrogen Shift of the Previtamin D-Vitamin D Equilibrium

pp.:  98 – 100

Synthesis and Biologic Evaluation of a Second Generation Photoaffinity Analog of 1,25-Dihydroxyvitamin D3

pp.:  100 – 102

Synthesis of the Unnatural (7Z)-Vitamin D Triene System

pp.:  102 – 104

Novel and Stereoselective Syntheses of 1α-Hydroxylated Vitamin D Metabolites

pp.:  104 – 106

On Oxidation of the Vitamin D Triene System – A Simple and Convenient Entry into the 19-Nor-10-Oxo-Derivatives of Vitamin D

pp.:  106 – 108

Synthesis of 25-Hydroxydihydrotachysterol2

pp.:  108 – 110

Stereochemistry at C(23) of 23,25-Dihydroxy-24-Oxovitamin D3

pp.:  110 – 112

Synthesis and Biological Activity of Highly Active Vitamin D Analogs: General Approaches to the Synthesis of Biologically Potent Vitamin D Sterols

pp.:  112 – 114

Syntheses of Labeled Side Chains of Vitamin D Metabolites and Analogs

pp.:  114 – 116

Synthesis of 22-Oxa-, and 20-Oxa-Analogues of Vitamin D3

pp.:  116 – 118

Computer Calculations of the Active Conformation of 1,25-Dihydroxy Vitamin D3

pp.:  118 – 121

Vitamin D Metabolism and Catabolism

pp.:  121 – 123

Precholecalciferol Formation by an Invertebrate, Psammechinus Miliaris

pp.:  123 – 133

Species Variation of Vitamin D Metabolism and Action: Lessons to be Learned from Farm Animals

pp.:  133 – 142

Metabolism of Vitamin D in Phagocytic Cells

pp.:  142 – 152

Extrarenal Production of Calcitriol in Chronic Renal Failure

pp.:  152 – 154

Metabolism of 1,25(OH)2D3 in Perfused Duodena from Normal Chicks

pp.:  154 – 156

Intestinal Metabolism of 25-Hydroxyvitamin D3: Effect of the X-Linked Hyp Mutation and 1,25-Dihydroxyvitamin D3 Treatment

pp.:  156 – 158

Biosynthesis of Water-Soluble Metabolites of 1,25-Dihydroxyvitamin D3 by Osteosarcoma UMR-106

pp.:  158 – 160

Conversion of 25-Hydroxyvitamin D3 to 19-Nor-10-Oxo-25-Hydroxyvitamin D3 by Solubilized Chick Kidney Mitochondria and Bovine Serum Albumin

pp.:  160 – 162

24-Oxidation of 1,25-(OH)2D3 by a Human Osteosarcoma Cell Line, U-20S

pp.:  162 – 164

The Vitamin D Depletion of Chronic Cholestasis is Independent of the Hepatic Metabolism of Vitamin D3

pp.:  164 – 166

Metabolic Clearance Rate and Production Rate of Calcitriol in Uremia. Effects of 25(OH)D Therapy

pp.:  166 – 168

Measurement of Production Rate and Metabolic Clearance Rate of 1,25- Dihydroxyvitamin D3 in Conscious Rats Using a Simplified Primed-Infusion Technique

pp.:  168 – 170

Metabolism of 1,25(OH)2D3 after Consecutive Dose of 1αOHD3 and 1,25(OH)2D3 in Rats

pp.:  170 – 172

25-Hydroxyvitamin D3 Sulphate in Human Plasma: Observations Using High Performance-Liquid Chromatography and Gas Chromatography-Mass Spectrometry

pp.:  172 – 175

The Effect of Vitamin D Status of Vitamin D Metabolism in Chicks

pp.:  175 – 177

Identification of a Subset of Dairy Cows that Fail to Produce 1,25-Dihydroxyvitamin D (1,25-(OH)2D) at the Onset of the Hypocalcemia Associated with Parturient Paresis

pp.:  177 – 179

The Intact Hepatocyte Hypothesis Applies to the C-25 Hydroxylation of Vitamin D3 in Alcoholic Cirrhosis

pp.:  179 – 181

Mechanism of Action of 26,27-Hexafluoro-1,25(OH)2D3

pp.:  181 – 183

1α, 25(OH)2D3-26,23-Lactone is a Major Metabolite of 1α, 25(OH)2D3 under Physiological Conditions

pp.:  183 – 185

25-Hydroxy-24-Oxovitamin D3 is a Natural Metabolite under Physiological Conditions

pp.:  185 – 187

Metabolism of 1,25(OH)2D3 after Single Intravenous or Oral Dose of 1αOHD3 and 1,25(OH)2D3 In Rats

pp.:  187 – 189

Administration of Pharmacological Amounts of 25(S), 26-Dihydroxyvitamin D3 Reduces 1,25-Dihydroxyvitamin D3 Synthesis

pp.:  189 – 191

The Effect of Growth Hormone on the Phosphate and Calcitriol Responses to Dietary Phosphorus Restriction in Man

pp.:  191 – 193

The Effect of Glutethimide on Rapidly Reducing the Circulating Concentration of 1,25-Dihydroxy Vitamin D in Hypervitaminosis D

pp.:  193 – 195

Biochemistry and Regulation of Hydroxylases

pp.:  195 – 197

Current Models for the Study of the Regulation of 25(OH)D3 Metabolism

pp.:  197 – 206

Solubilization and Reconstitution of Mammalian 25-OH-Vitamin D3-24 and 1α-Hydroxylase Activities from Pig Mitochondria

pp.:  206 – 208

Molecular Characterization of the Iron-Sulfur Protein from the Porcine Kidney Mitochondrial Hydroxylase System

pp.:  208 – 210

Normal Regulation of Calcitriol Production in Gy-Mice: Evidence for Biochemical Heterogeneity in the X-Linked Hypophosphatemic Diseases

pp.:  210 – 212

Regulation of 25-Hydroxyvitamin D3 Metabolism in Mitochondria Isolated from Primary Cultures of Chick Kidney Cells: Effects of Parathyroid Hormone and Forskolin

pp.:  212 – 214

The Stimulation of 25-Hydroxyvitamin D-1-Hydroxylase by Dietary Phosphorus Restriction Requires Insulin-Like Growth Factor-I (IGF-I)

pp.:  214 – 217

Phorbolic Ester Effect on Rat Renal 25-OHD3 1-Hydroxylase Activity: Possible Role of Ca, Phospholipid-Dependent Proteinkinase

pp.:  217 – 219

In Vitro Measurement of 25-Hydroxyvitamin D-1-Hydroxylase (1-OHase) Activity in Lactating Mice Using a New, Commercially Available Assay

pp.:  219 – 221

Inhibition of Renal Mitochondrial 25(OH)D-1-Hydroxylase Activity by Phosphorylation of Ferredoxin

pp.:  221 – 223

Protocol for Partial Purification of the Cytochrome P-450-1α

pp.:  223 – 225

Purification of a Cytochrome P-450 from Rabbit Liver Mitochondria Catalyzing 25-Hydroxylation of Vitamin D3

pp.:  225 – 227

Acute Changes in Perfusate Calcium and Phosphorus do not Affect 1-α-Hydroxylase Activity in the Isolated Perfused Rat Kidney

pp.:  227 – 229

Does the Administration of Phosphate Increase the Serum 1,25(OH)2D Concentration in X-Linked Hypophosphatemic Rickets?

pp.:  229 – 231

Ascorbic Acid Effects on 1-OHase and 24-OHase Activity in Kidney and 1,25(OH)2D3 Receptor Binding in Intestinal Mucosa of Guinea-Pigs

pp.:  231 – 234

Metabolism in Vitro of 25-Hydroxyvitamin D3 by Cultured Porcine Alveolar Macrophages

pp.:  234 – 236

Evidence that Rat Kidney 25-Hydroxyvitamin D-24-Hydroxylase Can Exist in an Inactive State

pp.:  236 – 238

25 Hydroxyvitamin D, 1α Hydroxylase (1-OH-Lase) Activity in Rhesus Monkeys

pp.:  238 – 240

25-Hydroxylation of Vitamin D3 by a Cytochrome P-450 from Pig Kidney Microsomes

pp.:  240 – 243

Receptors for 1,25(OH)2D3 (Biochemistry and Molecular Biology)

pp.:  243 – 245

Vitamin D Hormone Receptors: Structure, Regulation and Molecular Function

pp.:  245 – 255

Vitamin D3 Receptors: Molecular Structure of the Protein and its Chromosomal Gene

pp.:  255 – 265

Definition of the Funktional Domains of the Vitamin D3 Receptor

pp.:  265 – 267

Hyperthyroidism Increases Nuclear 1,25-Dihydroxyvitamin D3 Binding in Female Rat Liver

pp.:  267 – 269

Changes in Intestinal 1,25-Dihydroxyvitamin D Receptor Durning Aging, Gestation and Pregnancy in Rats

pp.:  269 – 271

Positive Cooperativity of the Rat Intestinal 1,25 Dihydroxyvitamin D Receptor

pp.:  271 – 273

Ketoconazole Potentiates 1,25-(OH)2D3-Directed Upregulation of 1,25-(OH)2D3-Receptors in Rat Intestine and Bone

pp.:  273 – 275

1α, 25-Dihydroxyvitamin D3 Receptor Defects in Lymphocyte Cell Lines from Vitamin D-Dependent Rickets Type II

pp.:  275 – 277

Vitamin K Role in the Interaction of 1,25(OH)2D3 Receptors with DNA

pp.:  277 – 280

Administration of 1,25-Dihydroxyvitamin D3 (1,25-(OH)2D3) Upregulates Number of Receptors for 1,25-(OH)2D in Colon Mucosa of Dairy Cows

pp.:  280 – 282

Characterization of the Chromosomal Gene of the Mouse Vitamin D Receptor

pp.:  282 – 284

Regulation of Vitamin D Action in Rat Osteogenic Sarcoma Cells (UMR-106)

pp.:  284 – 286

Duodenum and Colon 1,25-Dihydroxyvitamin D (1,25-(OH)2D) Receptor Concentration is Increased During Lactation in the Rat

pp.:  286 – 288

The 1,25-Dihydroxycholecalciferol Level in Plasma does not Influence the Properties of its Intestinal Receptor in Piglets

pp.:  288 – 290

The Number of 1,25-Dihydroxyvitamin D Receptors in Rat Intestinal Mucosa have been Markedly Underestimated

pp.:  290 – 296

DNA Binding Property of Vitamin D3 Receptors Associated with 26,26,26,27,27,27-Hexafluoro-1,25(OH)2D3

pp.:  296 – 298

Vitamin D3 Binding Protein of Phaseolus Vulgaris Roots. Biochemical and Functional Characterization

pp.:  298 – 301

Cell Differentiation / Hematopoiesis / Immunology

pp.:  301 – 303

Interaction between the Hematopoietic System and the Vitamin D Endocrine System

pp.:  303 – 307

1,25-(OH)2D3 and Gene Expression During HL-60 Differentiation

pp.:  307 – 316

Vitamin D: A Steroid Hormone of the Immune System, by the Immune System, for the Immune System

pp.:  316 – 322

Immunoregulatory Properties of 1,25(OH)2D3: Cellular Requirements and Mechanisms

pp.:  322 – 331

1,25-Dihydroxyvitamin D3 and the Regulation of Cancer Cell Replication

pp.:  331 – 340

MC 903 – A Novel Vitamin D Analogue with Potent Effects on Cell Proliferation and Cell Differentiation

pp.:  340 – 350

1α, 25-Dihydroxy-22-Oxavitamin D3: A New Synthetic Analogue of Vitamin D3 Having Potent Differentiation-Inducing Activity without Inducing Hypercalcemia in Vivo and in Vitro

pp.:  350 – 360

Mechanisms of Cell Fusion Induced by 1α,25-Dihydroxyvitamin D3

pp.:  360 – 370

1,25(OH)2D3 Promotes Differentiation of Resting Chondrocytes to Hypertrophic Cells in Vitro: A Model System for Evaluating the Potency of Vitamin D Analogs

pp.:  370 – 372

1α,25-Dihydroxyvitamin D3 Synthesis by Synovial Fluid Macrophages in Arthritic Disease

pp.:  372 – 374

1,25-Dihydroxyvitamin-D3 Prolongs Rat Cardiac Allograft Survival

pp.:  374 – 376

1,25-Dihydroxyvitamin D3 as a Synergistic Agent of in Vitro Cyclosporin A-Induced Suppressive Activity in Rheumatoid Arthritis

pp.:  376 – 378

Changes in Phosphoinositide Metabolism During 1,25(OH)2D3 Induced Cell Differentiation

pp.:  378 – 380

Increase in [Ca2+]i in Cultured Human Keratinocytes by 1,25(OH)2D3 is Calcium Dependent and Coincides with an Increase in Phosphatidylinositol Metabolism

pp.:  380 – 382

The Effects of 1α,25(OH)2D3, Diltiazem (D-Cis, L-Cis) on Induction of Differentiation of HL-60 Cells

pp.:  382 – 384

1α-Hydroxylated Vitamin D Metabolites Promote Differentiation and 24,25-Dihydroxy Vitamin D Synthesis in Human Leukaemia (HL60) Cells

pp.:  384 – 386

1,25 Dihydroxyvitamin-D3 Prolongs Skin Graft Survival in Mice

pp.:  386 – 388

Effects of 1,25(OH)2D3 on Myelopoiesis and B Lymphopoiesis in Long-term Marrow Cultures

pp.:  388 – 390

Vitamin D-Deficiency Disturbs the Differentiation Process in the Dental Papilla: An Ultrastructural Study

pp.:  390 – 392

1,25-Dihydroxyvitamin D3 Inhibits Delayed-Type Hypersensitivity Mediated by T-Cell Clones Inducing Experimental Autoimmune Encephalomyelitis

pp.:  392 – 394

1,25-Dihydroxyvitamin D3 Acts Directly on Human Lymphocytes and Interferes with the Cellular Response to Interleukin-2

pp.:  394 – 396

1α,25-Dihydroxyvitamin D3 Synthesis by Normal and Myelofibrotic Human Spleen Cells

pp.:  396 – 398

Pretreatment of T Cell or Monocytic Cell Lines with 1,25(OH)2D3 Markedly Increases IL2 or IL1 mRNA Levels Following Cell Activation

pp.:  398 – 400

Phorbol Ester Stimulation of 25OH-Vitamin D 1-Hydroxylase Activity in the Monoblastic Cell Line U937

pp.:  400 – 402

An Evaluation of Analogs of 1,25-Dihydroxyvitamin D3 on the Inhibition of Proliferation and Induction of Terminal Differentiation in Cultured Human Normal Keratinocytes

pp.:  402 – 404

1,25-Dihydroxyvitamin D3 Potentiates the Immunomodulatory Action of Prostaglandin E2 and Histamine by Interacting with cAMP-Dependent Pathways

pp.:  404 – 406

Effects of 1,25-Dihydroxyvitamin D3 and other Steroid Hormones on Protein Syntheses in Primary Cultures of Adult Rat Hepatocytes

pp.:  406 – 408

The Separation of Keratinocyte Populations Using a Gravity Sedimentation Chamber: A Potential Tool for the Study of 1,25(OH)2D3 Action on Cells at Different Stages of Differentiation

pp.:  408 – 410

Evidence that Osteoinduction by Implants of Demineralized Allogenic Bone Matrix is Diminished in Vitamin D-Deficient Normocalcemic Rats R. T. Turner, J. J. Vandersteenhoven, ?. H. Bell

pp.:  410 – 412

1,25(OH)2D3 Binds Specifically to Rat Vascular Smooth Muscle Cells and Stimulates their Proliferation in Vitro

pp.:  412 – 414

Involvement of Intracellular Free Calcium and pH in the Effect of 1,25(OH)2D3 on Leukemic Cells

pp.:  414 – 417

Gene Regulation by 1,25(OH)2D3

pp.:  417 – 419

Modifications in the Interactions of Regulatory Proteins with the Promoter of a Cell Growth Regulated Gene Induced to Differentiate by 1,25(OH)2D3

pp.:  419 – 421

Inhibition of 1,25-Dihydroxyvitamin D3 Stimulated BGP mRNA Synthesis in ROS 17/2 Cells after Prolonged Treatment with 1,25-Dihydroxyvitamin D3

pp.:  421 – 423

1,25(OH)2D Regulates Oncogene Expression in U937 Cells

pp.:  423 – 425

Regulation of Calbindin-D9K (CaBP9K) Gene Expression by 1,25-Dihydroxycholecalciferol and Calcium in Organ Cultures of Fetal Rat Duodenum

pp.:  425 – 427

Enhancement of the Genomic Action of 1,25-Dihydroxycholecalciferol by Triiodothyronine is a Regulatory Factor of Intestinal Calcium and Phosphate Transport

pp.:  427 – 429

Influence of Vitamin D3 upon the Expression of PEP-19, a Putative Neuron-Specific Calcium-Binding Protein

pp.:  429 – 431

Induction of Osteocalcin Synthesis in Human Osteosarcoma Cells by 1,25-Dihydroxyvitamin D and 24,24-Difluoro-1,25-Dihydroxyvitamin D

pp.:  431 – 433

Biological Actions of Vitamin D Metabolites

pp.:  433 – 435

The Role of 24,25 Dihydroxy Vitamin D3 During Development of Skeletal and Non-Skeletal Tissues

pp.:  435 – 445

The Regulation of Intracellular Ionized Calcium by Calcitriol

pp.:  445 – 456

Rapid Action of 1,25(OH)2D3 in Liver Cells

pp.:  456 – 459

1,25(OH)2D3 directly Modulates Human Melanocyte Function

pp.:  459 – 461

Stimulation of Synthesis of Myoblast Membrane Proteins by 25-Hydroxy- Vitamin D3

pp.:  461 – 463

Stimulation of Rat Duodenal Brush Border Alkaline Phosphatase Activity within 10 Minutes of in Vivo Calcitriol Administration

pp.:  463 – 465

1,25-Dihydroxy-Vitamin D3 Increases 3H-Thymidine-Uptake and Potentiates the Effect of Epidermal Growth Factor in FRTL-5 Cells

pp.:  465 – 467

1,25-Dihydroxyvitamin D3 Stimulates 45Ca2+ Uptake by Cultured Vascular Smooth Muscle Cells Derived from Rat Aorta

pp.:  467 – 469

1,25(OH)2D3 Activates Protein Kinase C in Rat Colonic Crypts

pp.:  469 – 471

Free 1,25-Dihydroxyvitamin D3 Levels in Normal and Rachitic Piglets

pp.:  471 – 473

1,25(OH)2 Vitamin D3 Analogs: Comparison of 1,25(OH)2D3 Receptor Ligand Specificity and Biological Activity in the Chick and Human Promyelocyte (HL-60) Cells

pp.:  473 – 475

24,25-Dihydroxy-Vitamin D3 Binding in Bovine Thyroid

pp.:  475 – 477

Effects of 1,25-Dihydroxy-Vitamin D3 on Phospholipid Metabolism in Cultured Myoblasts

pp.:  477 – 479

Vitamin D Status and Intestinal Absorption of Aluminum in Rats with Normal or Reduced Renal Function

pp.:  479 – 481

Direct Effect of Vitamin D Metabolites on Matrix Vesicle Alkaline Phosphatase

pp.:  481 – 483

Proliferative Effects of 1,25-Dihydrocholecalciferol (1,25-DHCC), 24,25-Dihydroxycholecalciferol (24,25-DHCC), 25-Hydroxycholecalciferol (25-HCC) and 1α-Hydroxycholecalciferol (1α-HCC)

pp.:  483 – 485

The Effect of Pertussis Toxin on PTH- and 1α,25(OH)2D3-Induced Desensitization in Rat Osteoblasts of the cAMP Response to PTH

pp.:  485 – 488

Synergistic Effects of Vitamin D3 Metabolites

pp.:  488 – 490

25(OH)D3, but not 1,25(OH)2D3 Cures Osteomalacia in Marmoset Monkeys

pp.:  490 – 492

Acute Release of Bioactive PTH by Intravenous 1,25 Dihydrocholecalciferol in Chronic Renal Failure

pp.:  492 – 494

1,25-Dihydroxy-Vitamin D3 Increases Calmodulin Binding to Skeletal Muscle Membrane Proteins

pp.:  494 – 496

Hypoparathyroidism in Hereditary Resistance to 1,25(OH)2D During Long-Term Treatment with Excessive Doses of Vitamin D3

pp.:  496 – 498

Effects of 1-alpha-OHD3 in Intestinal Radiocalcium Absorption and Serum Bone GLA Protein in Normal Subjects and Osteoporotic Women R. Nuti, V. Turchetti, G. Martini, G. Righi, F. Loré, A. Caniggia

pp.:  498 – 500

Rapid Effects of 1,25(OH)2-Vitamin D3 on Calcium Uptake by Cardiac Muscle

pp.:  500 – 502

1α, 25-Dihydroxyvitamin D3 in Rat Skin: Identification, Quantification and Biological Function

pp.:  502 – 504

1,25-Dihydroxyvitamin D3 Stimulates Ca-ATPase and Regulates Cellular Calcium in Vascular Smoosth Muscle Cells

pp.:  504 – 507

Calbindins (Biochemistry, Molecular Biology, Biological Actions)

pp.:  507 – 509

Calbindin-D9K (CaBP9K) Gene: Expression, Regulation, Structure and Evolution

pp.:  509 – 519

1,25-Dihydroxyvitamin D3, its Receptor and the Eukaryotic Genome

pp.:  519 – 529

Structure and Evolution of the Chick Calbindin Gene

pp.:  529 – 539

Regulation of Rat Calbindin-D28k Gene Expression

pp.:  539 – 547

Molecular Cloning and Sequencing of Calbindin-D9K cDNA from Mouse Placenta

pp.:  547 – 549

High Conservation of Calbindin D28 in Evolution: Implications for its Function

pp.:  549 – 552

Functional Analysis of the Promotor Region of the Gene Encoding Chicken Calbindin-D28K

pp.:  552 – 554

Cellular Localization of Brain Calbindin-D28k

pp.:  554 – 556

Vitamin D Dependence of Calbindin D 9K and Calbindin D 28K Synthesis in Various Rat Tissues

pp.:  556 – 558

Immunohistochemical Demonstration of Vitamin D-Dependent Calcium-Binding Protein, Calbindin-D 28K (CaBP28K) in the Spinal Cord Motoneurons of Teleost Fish

pp.:  558 – 560

In Situ Hybridization of the Rat Calbindin D-28

pp.:  560 – 563

Spectroscopic Studies on Chick Intestinal Calbindin-D28K Suggest the Existence of 4-6 Functional Ca2+ Binding Sites

pp.:  563 – 565

Evolution of the “EF-Hand” CaBP Family: Exon Shuffling and Intron Insertion

pp.:  565 – 567

Effects of Altered Thyroid States and Undernutrition on Calbindin-D28K (Calcium-Binding Protein) in the Hippocampal Formation of the Developing Rat

pp.:  567 – 569

Expression of Calbindin D Decreases with Age in Intestine and Kidney

pp.:  569 – 571

Evidence for Tissue-Specific Regulation of Calbindin 28K Gene Expression in the Chick by 1,25-Dihydroxyvitamin D3

pp.:  571 – 573

Evidence for the Presence of two Vitamin D-Dependent Calcium Binding Proteins in Brain

pp.:  573 – 575

The Human Calbindin D28 Gene

pp.:  575 – 577

Effect of Vitamin D Deficiency and 1,25-Dihydroxycholecalciferol Treatment on Epidermal Calcium Binding Protein (ECaBP) RNA Activity

pp.:  577 – 579

Complete Amino Acid Sequences of Mouse Calbindin-D9K Isoforms Determined by Tandem Mass Spectrometry: Protein Modification by Internal Insertion of a Single Amino Acid

pp.:  579 – 581

Developmental Pattern and Vitamin D-Dependency of the Calbindins CaBP 9KDa and CaBP 28KDa in the Ameloblasts of Rodent Teeth: An Immunocytochemical Study

pp.:  581 – 583

Calbindin (CaBP28kDa) Localization in the Peripheral Vestibular System of Various Vertebrates and Comparison with its Distribution During Development of the Mouse and Human

pp.:  583 – 585

Nuclear Magnetic Resonance and Terbium Fluorescence Studies on the Vitamin D-Dependent 28-Kilodalton Chick Intestinal Calcium-Binding Protein : Evidence for Calcium-Dependent Conformational Change

pp.:  585 – 587

Intestinal and Renal Ca and P Transport

pp.:  587 – 589

Transcaltachia, Vesicular Calcium Transport, and Microtubule-Associated Calbindin-D28K

pp.:  589 – 598

Vitamin D: Effects on Intestinal Calcium Absorption and Peripheral Nerve Function

pp.:  598 – 605

ATP-Dependent Ca2+ Pumps in Endoplasmic Reticulum and Plasma Membranes are not Affected by 9kDa Calbindin-D and Vit. D-Deficiency

pp.:  605 – 607

Effects of Vitamin D-Deficiency on Different Activities of the Ca2+-Pump in Rat Intestinal Basolateral Membranes

pp.:  607 – 609

ATP-Driven Ca2+ Pumps in Duodenal Plasma Membranes and Endoplasmic Reticulum from Piglets with Inherited Rickets

pp.:  609 – 611

Effect of 1,25(OH)2D3 on Phosphorus Absorption in Sheep

pp.:  611 – 613

Reduced Calcium Absorption in X-Linked Hypophosphatemic Rickets

pp.:  613 – 615

Phosphate Transport in the Intestine of the Rat During Early Development: Role of Vitamin D

pp.:  615 – 617

The 105kD Calmodulin (CAM) Binding Protein from Intestinal Brush Border Membrane (BBM) is a Calcium Transport Protein

pp.:  617 – 619

Bone and Action of Vitamin D Metabolites

pp.:  619 – 621

The Role of 1,25-Dihydroxyvitamin D3 in the Generation and Regulation of Osteoclasts

pp.:  621 – 631

Vitamin D and Osteoclastogenesis

pp.:  631 – 636

Dentin Formation and Plasma Ca Levels in PTX Rats given 1,25(OH)2D3

pp.:  636 – 638

Elevated 1,25-Dihydroxyvitamin D3 and Intestinal Calbindin-D9K Levels in the Osteopetrotic Toothless Rat

pp.:  638 – 640

Influence of 24-Fluorinated Analogues of 1,25(OH)2D3 on Bone Matrix Formation and Bone Resorption in Vitro

pp.:  640 – 642

Modulation of the Action of 1,25(OH)2D3 on the Osteocalcin Production of Human Osteoblast-Like Cells by Agents Affecting Adenylate Cyclase Activity

pp.:  642 – 644

Increased Bone Minerals in Vitamin D-Replete Rabbit by the Massive Administration of 24R,25(OH)2D3

pp.:  644 – 646

Studies on the Interactions between Retinoic Acid and 1,25(OH)2D3 on Human Bone-Derived Osteoblast-Like Cells

pp.:  646 – 648

Immunosuppressive Agent Cyclosporin A and Various Cell Growth Factors Affect Cloned Osteoblastic Cell Line MC3T3-E1 Cells

pp.:  648 – 650

23(S)25(R)-1,25(OH)2D3-26,23-Lactone Stimulates Bone Formation in Vivo

pp.:  650 – 652

Side Chain Modifications Increase the Potency of 1,25-Dihydroxy- cholecalciferol (Calcitriol) on Human Bone-Derived Osteoblast-Like Cells

pp.:  652 – 654

Activity of Ornithine Decarboxylase in Hard Tissue of Vitamin D-Deficient and -Replete Rats: Effect of 1,25(OH)2D3, Uremia and Aluminum Intoxication

pp.:  654 – 656

Production of Bone-Resorbing and Osteoclast-Inducing Factors by Osteoblasts in Organ Culture and Modulation by 1,25(OH)2D3 and other Agonists

pp.:  656 – 658

Circulating Osteocalcin in Magnesium Deficiency: Response to 1,25(OH)2D

pp.:  658 – 660

1,25(OH)2D3 Mediates the Effect of Parathyroid Hormone on New Bone Formation in the Rat

pp.:  660 – 662

Circulating Osteocalcin and 1,25-Dihydroxyvitamin D Concentrations and Urinary γ-Carboxyglutamic Acid in Healthy Subjects and in Patients with Metabolic Bone Disease

pp.:  662 – 664

Regulation of Fibronectin and Collagen Synthesis by 1,25-Dihydroxyvitamin D3

pp.:  664 – 666

1,25-Dihydroxyvitamin D3 Stimulates in Vitro Growth of Avian and Mammalian Cartilage

pp.:  666 – 669

Nutritional Aspects of Vitamin D

pp.:  669 – 671

Minimal Intravenous Vitamin D Requirement During Parenteral Nutrition in Infancy

pp.:  671 – 673

Serum 25(OH)D3 and 1,25(OH)2D3 Levels in Wild and Laboratory-Bred Wood Mice and Bank Voles

pp.:  673 – 675

Effect of Acute Ethanol Administration on the Circulating Parameters of Bone Mineral Metabolism

pp.:  675 – 677

Plasma 25-OHvitamin D and PTH in the Detection of Osteomalacia in Asian Outpatients

pp.:  677 – 680

The Vitamin D Content of Finnish Hospital Diets

pp.:  680 – 682

Zinc, Vitamin D and Bone Mass in the Elderly

pp.:  682 – 684

The Importance of Vitamin C for Hydroxylation of Vitamin D3 to 1α,25(OH)2D3 and of 24R,25(OH)2D3 to a More Active Metabolite

pp.:  684 – 694

Plasma Magnesium in Pigs with Pseudo Vitamin D Deficient Rickets; Type 1

pp.:  694 – 696

Sunlight Degradation of Vitamin D3

pp.:  696 – 698

Fatty Acid and Calcium Absorption in Rats. Role of Vitamin D

pp.:  698 – 700

Clinical Studies on the Mechanism of Acquired Vitamin D Deficiency

pp.:  700 – 702

How is Plasma 1,25(OH)2D3 Concentration Regulated by Dietary Calcium?

pp.:  702 – 704

Studies of Rickets and its Prevention in Beijing, China

pp.:  704 – 707

Vitamin D Binding Proteins

pp.:  707 – 709

DBP and AIDS: Fact or Fiction?

pp.:  709 – 714

Plasma Vitamin D Binding Protein: Plasma Scavenger Function and Origin of Cell-Surface DBP

pp.:  714 – 720

Partial Structure of the Gene for Human Vitamin D-Binding Protein

pp.:  720 – 725

A New Interaction between Gc (Vitamin D-Binding Protein) and Unsaturated Fatty Acids

pp.:  725 – 732

Two 25-Hydroxycholecalciferol-Binding Proteins in Carp Serum

pp.:  732 – 734

HPLC Analysis of the Cyanogen Bromide Digest of Human Serum Vitamin D Binding Protein Photoaffinity Labelled with a 25-Hydroxyvitamin D3 Analog

pp.:  734 – 736

Effect of Calcium Ions upon Interactions between Gc (Vitamin D-Binding) Protein and Cibacron Blue

pp.:  736 – 738

Partial Purification and Properties of Bat Vitamin D Binding Protein Meropi Cavaleros

pp.:  738 – 741

Assay Methodology: Vitamin D and Metabolites

pp.:  741 – 743

Measurement of Free Vitamin D Metabolite Levels: Biological and Clinical Significance

pp.:  743 – 750

The Assay of Circulating 1,25(OH)2D using Non-End-Capped C18 Silica (C18-OH): Performance and Validation

pp.:  750 – 760

Simplified Assays for the Determination of 25-OHD, 24,25(OH)2D and 1,25(OH)2D

pp.:  760 – 767

Stable Isotope Dilution Mass Fragmentography for the Measurement of Metabolites of Vitamins D2 and D3 in Human Plasma

pp.:  767 – 768

Well Established Physiological Functions are a Prequisite for Introducing Biochemical Parameters

pp.:  768 – 770

The Quantification of Serum 25-Hydroxyvitamin D Using a Competitive Protein-Binding Assay after Preliminary Purification

pp.:  770 – 772

Changes in Plasma Levels of Vitamin D2, D3 and Their Metabolites after Oral Administration of the Vitamins to Vitamin D-Deficient Rats

pp.:  772 – 774

Age-Related Changes in Immunoradiometric PTH and 25-Hydroxy- vitamin D

pp.:  774 – 775

Relevance of Long-Term Variation in Vitamin D Metabolite Measurements. Implications for Longitudinal Study Design

pp.:  775 – 777

Other Basic Science Topics

pp.:  777 – 779

Prospects for the Modelling of Vitamin D Activity in Man

pp.:  779 – 789

Isolated Rat Proximal Tubule Cell (PTC) Cultures are cAMP Responsive to Parathyroid Hormone (PTH), Calcitonin (CT), and Prostaglandins (PGE) but not to Vasopressin (VP)

pp.:  789 – 791

Lipid Composition of Basolateral Membranes from Rat Enterocytes: Effects of Vitamin D Deficiency

pp.:  791 – 793

Possible Origin of Extremely Large Amounts of Vitamin D3 in Some Kinds of Fish Liver

pp.:  793 – 795

Hepatotoxic Effects of Aluminium: Implications for Vitamin D Metabolism

pp.:  795 – 797

Studies on Kinetics of Previtamin D Formation Reaction, Effects of Irradiation Intensity at 296nm on Previtamin D Formation Zhiren Lu, Yafang Pang, Chengfa Zheng

pp.:  797 – 800

Vitamin D Deficiency and Cardiac Function in Isolated Chick Hearts

pp.:  800 – 802

Vitamin D Effects on Ca-Stimulated ATPase Activity and Protein Composition of the Rat’s Skeletal Muscle Miofibrills

pp.:  802 – 803

The Spontaneously Hypertensive Rat (SHR): A Model of Abnormal Vitamin D Metabolism

pp.:  803 – 805

Vitamin D3- and Stigmasterol-Induced Calmodulin Synthesis in Phaseolus Vulgaris Roots is Mediated by Ca+2 and Plant Growth Hormone-Like Mitogenic Stimulation

pp.:  805 – 807

A Very Rapid Receptor Mediated Action of 1,25-Dihydroxyvitamin D3: Increase of Intracellular Cyclic GMP in Human Skin Fibroblasts

pp.:  807 – 809

Effects of Vitamin D3 Metabolites on Cytosolic Free Calcium in Confluent Mouse Osteoblasts: A Possible Involvement of Protein Kinase C Michèle Lieberherr

pp.:  809 – 819

Renal Osteodystrophy

pp.:  819 – 821

Plasma Kinetics of Intravenous Calcitriol in Normal and Dialysed Subjects and Acute Effect on Serum nPTH Levels

pp.:  821 – 823

Bioavailability of Calcitriol after Oral, Intravenous and Intraperitioneal Doses in Dialysis Patients

pp.:  823 – 825

Intravenous Administration of 1α-Hydroxycholecalciferol in Haemodialysed Patients: Dose-Dependent Increase in Circulating 1,25-Dihydroxycholecalciferol

pp.:  825 – 827

Ten Years Experience in the Prevention of Renal Osteodystrophy by Vitamin D-Prophylaxis

pp.:  827 – 829

Successful Treatment of Renal Osteodystrophy with Keto Acids (KA) and Vitamin D

pp.:  829 – 831

Effect of 1,25(OH)2D3 and 24R,25(OH)2D3 on the Accumulation of Aluminum in Bone in Rats with Renal Failure

pp.:  831 – 833

The Influence of Vitamins D2 and D3 on Intestinal Calcium Absorption in Patients with Renal Insufficiency and in Dialysis Patients

pp.:  833 – 835

1α(OH)D3 i.v. Suppression of PTH Secretion in Hemodialysis Patients

pp.:  835 – 837

Clinical and Biochemical Effects of 1,25-Dihydroxyvitamin D3 Administration in Normal and Renal Impaired Dogs

pp.:  837 – 839

Hyper- and Normo- Calcemic Dogs with Chronic Renal Failure: Relations of Serum PTH and Calcitriol to PTG Ca++ Set-Point

pp.:  839 – 841

Dietary Intake and Status of Vitamin D and Calcium in Patients with Chronic Renal Failure (CRF) Treated by Haemodialysis (HD) at home

pp.:  841 – 843

Osteocalcin (OC) in Adolescents with Advanced Renal Failure

pp.:  843 – 845

Osteoporosis

pp.:  845 – 847

Long-Term Calcitriol Treatment in Post-Menopausal Osteoporosis: Follow-Up of two Hundred Patients

pp.:  847 – 857

Osteoporosis and Vitamin D Metabolism: The State of our Knowledge as of 1988

pp.:  857 – 866

The Rationale for Calcitriol Therapy in Osteoporosis

pp.:  866 – 876

Calcitriol Therapy in the Management of Osteoporosis

pp.:  876 – 878

Alfacalcidol in Prednisone Treatment: Effect on Bone Mineral Content in Lumbar Spine and Femur

pp.:  878 – 880

Decrease of Plasma 1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) and Loss of Spinal Bone Mass in Women During Treatment with GnRH Agonists

pp.:  880 – 882

Effect of 26,27-Hexafluoro-1,25-Dihydroxyvitamin D3 (F6-1,25(OH)2D3) on Osteoporosis Induced by Immobilization Combined with Ovariectomy in the Rats

pp.:  882 – 884

Some Biochemical Markers in Distal Fore-Arm and Hip Fractures

pp.:  884 – 886

The Short Term Effects of Alfacalcidol in Elderly Osteoporotic Women

pp.:  886 – 888

Calcitonin Secretion in Osteoporosis of Turner Syndrome

pp.:  888 – 890

Determinants of Calcium Malabsorption in Postmenopausal Osteoporosis

pp.:  890 – 893

Sarcoidosis

pp.:  893 – 895

Regulated Expression of the Sarcoid Macrophage 25-Hydroxyvitamin D-1-Hydroxylation Reaction

pp.:  895 – 897

Accentuated Transpleural Gradient of “Total” and “Free” 1,25-Dihydroxyvitamin D in Patients with Tuberculous Pleuritis

pp.:  897 – 899

The Effects of Ketoconazole and Metyrapone on Activated Alveolar Macrophages

pp.:  899 – 901

1,25(OH)2D3 Production by Lung T Lymphocytes from Tuberculosis Patients

pp.:  901 – 903

Cancer and Vitamin D

pp.:  903 – 905

Treatment of Myelodysplastic Syndrome and AML with 1α Hydroxyvitamin D3

pp.:  905 – 907

Nude Mouse Model (CAC-8) of Humoral Hypercalcemia of Malignancy (HHM) with Increased Serum Levels of 1,25-Dihydroxycholecalciferol (1,25(OH)2D): In Vivo and in Vitro Studies

pp.:  907 – 909

Effects of Treatment with the Bisphosphonate APD on 1,25-Dihydroxyvitamin D in Patients with Malignant Hypercalcaemia

pp.:  909 – 911

Effect of 1α-Hydroxyvitamin D3 on Growth of Nitrosomethylurea-Induced Rat Mammary Tumors

pp.:  911 – 913

Diabetes and Vitamin D

pp.:  913 – 915

Interaction between Vitamin D, Insulin and Diabetes Mellitus

pp.:  915 – 925

Endogenous Diabetes Decreases the Number of 1,25-Dihydroxyvitamin D3 Receptors in both Intestine and Kidney

pp.:  925 – 927

Plasma Concentrations of Vitamin D Metabolites in Newly Diagnosed Young Insulin-Dependent Diabetics before and after Insulin Treatment

pp.:  927 – 929

The Effect of Hypocalcemia and Vitamin D-Deficiency on Glucose Utilization in Piglets

pp.:  929 – 931

Vitamin D-Induced Increase in Calcium Content in Secretory Granules of B Cells Plays a Role in Recovery of Insulin Secretion in Vitamin D-Deficient Rats

pp.:  931 – 933

Increase in Insulin Response to Glucagon Following UV-B Irradiation in Healthy Adults

pp.:  933 – 937

Serum 1,25(OH)2D3 in the Elderly and Osteoporotic Subjects from Southern Italy. A Preliminary Report

pp.:  937 – 939

Gerontology and Vitamin D

pp.:  937 – 937

Effect of Age on the Rat Intestinal 1,25(OH)2D3 Receptor

pp.:  939 – 941

Effect of Age and 1,25(OH)2D3 on Calcium Uptake in Rat Duodenum Cells

pp.:  941 – 943

Low Serum Concentrations of 25-Hydroxyvitamin D, Selenium and Osteocalcin in Finnish Elderly Men

pp.:  943 – 945

Response of the Serum Level of 1,25(OH)2D to Restriction of Dietary Phosphorus: Effect of Advanced Age

pp.:  945 – 947

Intestinal End-Organ Resistance to 1,25-Dihydroxyvitamin D Stimulation of Calcium Absorption in the Senescent Rat

pp.:  947 – 949

Pregnancy/Neonatology

pp.:  949 – 951

Serum Vitamin D, 25-OHD, and 1,25(OH)2D, Bone Mineral Content (BMC) and Mineral Homeostasis in Premature Infants Fed High Mineral Premature Formula

pp.:  951 – 953

Normal Plasma 1,25(OH)2D3 in a Breast Fed Premature Infant with Early Hypophosphatemic Rickets

pp.:  953 – 955

Changes in 1,25-Dihydroxyvitamin D3 Receptor (1,25 DR) Content of Rat Mammary Gland During Pregnancy and Lactation

pp.:  955 – 957

Concentration of Vitamin D Metabolites in Amniotic Fluid and Serum During Pregnancy

pp.:  957 – 959

1,25(OH)2D3 and Ostoecalcin Concentrations in Fetuses and Neonates from Rats Fed two Different Calcium-Phosphate Diets

pp.:  959 – 961

Intact PTH and Vitamin D Metabolites in Early Neonatal Hypocalcemia

pp.:  961 – 963

Other Clinical Topics

pp.:  963 – 965

Vitamin D and the Skin: Site of Synthesis, Target Tissue, and New Therapeutic Approach for Psoriasis

pp.:  965 – 975

Inborn Errors in Vitamin D Metabolism – Their Contribution to the Understanding of Vitamin D Metabolism

pp.:  975 – 988

Vitamin D and Human Antituberculosis Immunity

pp.:  988 – 998

Successful Treatment of Psoriasis with Topical Application of the Active Vitamin D3 Analog, 1α,24-Dihydroxycholecalciferol (TV-02)

pp.:  998 – 1008

Evidence that Alteration of the Vitamin D-Endocrine System in Obesity Results from Vitamin D Deficiency

pp.:  1008 – 1016

Abnormal 1,25(OH)2D3 Receptor Relation of Parathyroid Gland in Lead Intoxication

pp.:  1016 – 1017

Hypocalcemia and Decreased 1,25(OH)2D Blood Levels in Septic Patients

pp.:  1017 – 1019

Serum Vitamin D and Calcium Metabolism in Tuberculosis Patients Resident in two Tropical Environments

pp.:  1019 – 1021

Abnormal Vitamin D Metabolism in Primary Aldosteronism and Experimental Mineralocorticoid Excess

pp.:  1021 – 1023

Vitamin D Metabolites and Intact PTH in Spasmophilia

pp.:  1023 – 1025

Vitamin D Status in Patients with Cystic Fibrosis: Seasonal Variations and the Importance of Vitamin D Supplementation:

pp.:  1025 – 1027

An Epidemiological Association between Vitamin D Deficiency and Tuberculosis

pp.:  1027 – 1029

Conversion of 1α-OHD3 into 1,25(OH)2D3 in Normal Subjects, Cirrhotic Patients and Postmenopausal Osteoporotic Women

pp.:  1029 – 1031

The Role of 1,25-Dihydroxyvitamin D in Salt Sensitive Essential Hypertension: Effects of Calcium Channel Blockade

pp.:  1031 – 1033

Vitamin D3 Induced Glycolic Aciduria in an Experimental Stone Model A. Halabe, N. L. M. Wong, L. Hagen, H. Hughes, R. A. L. Sutton

pp.:  1033 – 1035

Vitamin D Metabolism in Benign Transient Hyperphosphatasaemia

pp.:  1035 – 1037

Serum Calcium can Modulate the Production of 1,25-Dihydroxyvitamin D Independently of PTH in Man

pp.:  1037 – 1039

Age-Dependent Changes of Vitamin D Status and 1,25(OH)2D3 Receptor Expression in Spontaneously Hypertensive (SH) Rats

pp.:  1039 – 1041

Behavioral Changes in Chronically D-Hypervitaminotic Animals

pp.:  1041 – 1047

1,25-Dihydroxyvitamin D3 is an Effective Therapeutic Agent for the Treatment of Psoriasis Vulgaris and Erythroderma Psoriasis

pp.:  1047 – 1049

Vitamin D, Calcium and Hypertension

pp.:  1049 – 1053

Dietary Vitamin D Level and Mineral (P, Ca) Absorption in Pigs Fed Phytic P Diets

pp.:  1053 – 1055

Effect of Active Vitamin D3 on Enterocytes and Fatty Acid Binding Substance in Microsomal Fraction of Intestinal Mucosa of Rats

pp.:  1055 – 1057

Vitamin D Therapy in Renal Failure – Challenges and Problems for the Future

pp.:  1057 – 1061

Synthesis of 24R,25-Dihydroxyvitamin D3 from Vitamin D2 and Study on Inclusion Complexes of Vitamin D Derivatives with β-Cyclodextrin

pp.:  1061 – 1065

Author Index

pp.:  1065 – 1073

Key Word Index

pp.:  1073 – 1107

Cell Line Index

pp.:  1107 – 1109

Vitamin D Workshop Zoo

pp.:  1109 – 1111

Summary of the Dates and Locations of the Seven Vitamin D Workshops

pp.:  1111 – 1112

Vitamin D Workshop Logo

pp.:  1112 – 1117

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