Development and Aging in the Nervous System

Author: Rockstein   Morris  

Publisher: Elsevier Science‎

Publication year: 2012

E-ISBN: 9780323159661

P-ISBN(Paperback): 9780125916509

P-ISBN(Hardback):  9780125916509

Subject: Q426 central nervous system physiology

Language: ENG

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Description

Development and Aging in the Nervous System covers the proceedings of a series of symposia by the same title, held at the University of Miami Training Program in Cellular Aging on February 19-20, 1973. This book is composed of 11 chapters that specifically consider aging in its total sense, from embryonic development through senescence of a vital organ system of the body.

The introductory chapters review the age changes in the neuronal microenvironment and the regulative mechanism of neuronal death in cell number control in the nervous system. The next chapters deal with the neuronal degeneration in aging mammals, the selected changes in the developing postnatal rat, and the trophic influences in the mammalian central nervous system. These topics are followed by discussions of the genesis of neuronal locus specificity, the vertebrate brain aging, and the neurochemical patterns in the developing and aging brain. The remaining chapters describe the mechanisms of enzymatic differentiation in the brain and in cultured cells and the monoamine metabolism in the aging male mouse.

This book will prove useful to development and cell biologists, researchers, and advance students.

Chapter

Front Cover

pp.:  1 – 4

Copyright Page

pp.:  5 – 6

Table of Contents

pp.:  6 – 8

CONTRIBUTORS

pp.:  8 – 10

PREFACE

pp.:  10 – 14

CHAPTER 1. AGE CHANGES IN THE NEURONAL MICROENVIRONMENT

pp.:  14 – 32

CHAPTER 2. NEURONAL DEATH AS A REGULATIVE MECHANISM IN THE CONTROL OF CELL NUMBER IN THE NERVOUS SYSTEM

pp.:  32 – 56

CHAPTER 3. NEURONAL DEGENERATION IN AGING MAMMALS

pp.:  56 – 76

CHAPTER 4. SELECTED CHANGES IN THE DEVELOPING POSTNATAL RAT BRAIN1

pp.:  76 – 102

CHAPTER 5. TROPHIC INFLUENCES IN THE MAMMALIAN CENTRAL NERVOUS SYSTEM

pp.:  102 – 118

CHAPTER 6. GENESIS OF NEURONAL LOCUS SPECIFICITY

pp.:  118 – 134

CHAPTER 7. AGING OF THE VERTEBRATE BRAIN

pp.:  134 – 148

CHAPTER 8. INSULTS TO THE BRAIN. DIFFERENTIAL EFFECTS OF AGING

pp.:  148 – 164

CHAPTER 9. NEUROCHEMICAL PATTERNS IN THE DEVELOPING AND AGING BRAIN

pp.:  164 – 184

CHAPTER 10. MECHANISMS OF ENZYMATIC DIFFERENTIATION IN THE BRAIN AND IN CULTURED CELLS

pp.:  184 – 212

CHAPTER 11. MONOAMINE METABOLISM IN THE AGING MALE MOUSE

pp.:  212 – 232

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