Drugs and the Cell Cycle

Author: Zimmerman   A  

Publisher: Elsevier Science‎

Publication year: 2012

E-ISBN: 9780323155014

P-ISBN(Paperback): 9780127812601

P-ISBN(Hardback):  9780127812601

Subject: Q26 cellular biochemistry

Language: ENG

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Description

Drugs and the Cell Cycle provides an introduction to fundamental principles and studies on the mechanisms of drug action on proliferating cells. The book is intended to reduce the time lag between observation and practical application.

Comprised of 10 chapters, the book describes the plant alkaloids, alkylating agents, mercurials, adrenergic agents, radiomimetics, narcotics, hallucinogens, mitogens, hepatotoxins, antiobiotics, and antimetabolites of various types. The text also emphasizes the drugs used in cancer chemotherapy, and the in vitro and in vivo cell systems of bacteria, protozoa, sea urchins, and mammals. The concepts are presented with comprehensive illustrations and tables to help readers obtain more efficient understanding and learning.

The information and concepts presented in this volume will be of great interest to scientists and students in many disciplines, including physiology, pharmacology, and oncology, as well as cellular, molecular, and developmental biology. The book will also fill the gap between drug experimental observations and their potential relevance to man.

Chapter

Front Cover

pp.:  1 – 4

Drugs and the Cell Cycle

pp.:  4 – 5

Copyright Page

pp.:  5 – 6

Table of Contents

pp.:  6 – 10

List of Contributors

pp.:  10 – 12

Preface

pp.:  12 – 14

Chapter 2. Macromolecular Assembly Inhibitors and Their Action on the Cell Cycle

pp.:  24 – 38

Chapter 3. The Effect of Mercuric Compounds on Dividing Cells

pp.:  38 – 62

Chapter 4. Adrenergic Drugs on the Cell Cycle

pp.:  62 – 80

Chapter 5. Action of Narcotic and Hallucinogenic Agents on the Cell Cycle

pp.:  80 – 108

Chapter 6. Effects of Drugs on Hepatic Cell Proliferation Abbreviations

pp.:  108 – 150

Chapter 7. Effects of Mitogens on the Mitotic Cycle: A Biochemical Evaluation of Lymphocyte Activation

pp.:  150 – 208

Chapter 8. Intestinal Cytodynamics: Adductions from Drug Radiation Studies

pp.:  208 – 232

Chapter 9. The Effects of Antitumor Drugs on the Cell Cycle

pp.:  232 – 262

Chapter 10. Effects of Purines, Pyrimidines, Nucleosides, and Chemically Related Compounds on the Cell Cycle

pp.:  262 – 320

AUTHOR INDEX

pp.:  320 – 337

SUBJECT INDEX

pp.:  337 – 345

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