Strategies and Tactics In Organic Synthesis

Author: Lindberg   Thomas  

Publisher: Elsevier Science‎

Publication year: 2012

E-ISBN: 9780323152938

P-ISBN(Paperback): 9780124502802

P-ISBN(Hardback):  9780124502802

Subject: O62 Organic Chemistry

Language: ENG

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Description

Strategies and Tactics in Organic Synthesis presents the chronological development of ideas and experimentation in organic synthesis. This book is organized into 13 chapters that explore the synthetic pathways of various organic compounds.
The first four chapters describe the variations in the synthesis of superphane, gibberellic acid, prostaglandin, and alkaloids. The following chapters cover the organic synthesis and biosynthesis of tylonolide, endiandric acids A-G, dodecahedrane, fomannosin, and illudol. A chapter focuses on the evolution of the total synthesis of jatrophone, an architecturally interesting macrocyclic diterpene extracted from Jatropha gossypiifolia. Another chapter discusses the heuristic principle for the stereorationale design of alkaloid syntheses. The remaining chapters discuss the approach to the total synthesis of steroids, streptonigrin, methynolide, and Prelog-Djerassi lactonic acid.
Organic chemists, teachers, and students will find this book of great value.

Chapter

Front Cover

pp.:  1 – 4

Copyright Page

pp.:  5 – 6

Table of Contents

pp.:  6 – 12

CONTRIBUTORS

pp.:  12 – 14

PREFACE

pp.:  14 – 16

CHAPTER 2. THE TOTAL SYNTHESIS OF GIBBERELLIC ACID

pp.:  36 – 86

CHAPTER 3. A PROSTAGLANDIN SYNTHESIS

pp.:  86 – 98

CHAPTER 4. SYNTHESIS OF INDOLE ALKALOIDS

pp.:  98 – 138

CHAPTER 5. SYNTHESIS OF TYLONOLIDE, THE AGLYCONE OF TYLOSIN

pp.:  138 – 170

CHAPTER 6. PERICYCLIC REACTIONS IN ORGANIC SYNTHESIS AND BIOSYNTHESIS: SYNTHETIC ADVENTURES WITH ENDIANDRIC ACIDS A – G

pp.:  170 – 190

CHAPTER 7. PLATO'S SOLID IN A RETORT: THE DODECAHEDRANE STORY

pp.:  190 – 216

CHAPTER 8. THE SYNTHESIS OF FOMANNOSIN AND ILLUDOL

pp.:  216 – 238

CHAPTER 9. EVOLUTION OF A SYNTHETIC STRATEGY: TOTAL SYNTHESIS OF JATROPHONE

pp.:  238 – 290

CHAPTER 10. ON THE STEREOCHEMISTRY OF NUCLEOPHILIC ADDITIONS TO TETRAHYDROPYRIDINIUM SALTS: A POWERFUL HEURISTIC PRINCIPLE FOR THE STEREORATIONALE DESIGN OF ALKALOID SYNTHESES

pp.:  290 – 314

CHAPTER 11. A NONBIOMIMETIC APPROACH TO THE TOTAL SYNTHESIS OF STEROIDS: THE TRANSITION METAL-CATALYZED CYCLIZATION OF ALKENES AND ALKYNES

pp.:  314 – 340

CHAPTER 12. EVOLUTION OF A STRATEGY FOR TOTAL SYNTHESIS OF STREPTONIGRIN

pp.:  340 – 362

CHAPTER 13. METHYNOLIDE AND THE PRELOG-DJERASSI LACTONIC ACID: AN EXERCISE IN STEREOCONTROLLED SYNTHESIS

pp.:  362 – 382

INDEX

pp.:  382 – 386

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