Anti-inflammatory Agents Part II :Chemistry and Pharmacology

Publication subTitle :Chemistry and Pharmacology

Author: Scherrer   Robert  

Publisher: Elsevier Science‎

Publication year: 2012

E-ISBN: 9780323152112

P-ISBN(Paperback): 9780126239027

P-ISBN(Hardback):  9780126239027

Subject: R978 drug in the treatment of infectious and parasitic diseases

Language: ENG

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Description

Medicinal Chemistry: A Series of Monographs, Volume 13–II presents the context of inflammation and the therapeutic interventions in debilitating chronic inflammatory diseases. This book discusses the progress of therapeutics in the field of medicine with less cost but with the same degree of benefit.
Comprised of 10 chapters, this volume begins with a discussion on the pathophysiological context of chronic inflammatory diseases. This book then explores the local hormones that act as alarm signals following a local injury, which includes serotonin, histamine, kinins, heparin, prostaglandin, adenylates, lysolecithins, and catecholamines. Other chapters feature contributors who have active research on the clinical evaluation and treatment of severely debilitating chronic inflammatory diseases, including gout, arthritis, rheumatoid arthritis, osteoarthritis, psoriasis, and systemic lupus erythematosus. The final chapter explores the metabolism of anti-inflammatory drugs that are organized around chemical classes of compounds.
This book is a valuable source of information for physicians, chemists, and experimental biologists.

Chapter

Front Cover

pp.:  1 – 4

Copyright Page

pp.:  5 – 8

Table of Contents

pp.:  8 – 12

List of Contributors

pp.:  12 – 14

Preface

pp.:  14 – 16

Contents of Volume I

pp.:  16 – 18

Chapter 2. Evaluation for Antiinflammatory Activity

pp.:  52 – 142

Chapter 3. Evaluation for Immunosuppressive and Antiallergic Activity

pp.:  142 – 212

Chapter 4. Assessment of the Toxicity of Antiinflammatory Drugs

pp.:  212 – 236

Chapter 5. Evaluation for Clinical Efficacy

pp.:  236 – 254

Chapter 6. Drug Kinetic Studies with Nonsteroidal Antiinflammatory Agents in Animals and Man

pp.:  254 – 264

Chapter 7. Inhibition of Blood Platelet Function

pp.:  264 – 282

Chapter 8. Molecular and Cellular Pharmacology of the Antiinflammatory Drugs: Some in Vitro Properties Related to Their Possible Modes of Action

pp.:  282 – 322

Chapter 9. Some Effects of Antiinflammatory Drugs on Connective Tissue Metabolism

pp.:  322 – 346

Chapter 10. Metabolism of Selected Antiinflammatory Compounds

pp.:  346 – 366

Author Index

pp.:  366 – 392

Subject Index

pp.:  392 – 402

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