Glucuronic Acid Free and Combined :Chemistry, Biochemistry, Pharmacology, and Medicine

Publication subTitle :Chemistry, Biochemistry, Pharmacology, and Medicine

Author: Dutton   Geoffrey  

Publisher: Elsevier Science‎

Publication year: 2012

E-ISBN: 9780323143981

P-ISBN(Paperback): 9780123955012

P-ISBN(Hardback):  9780123955012

Subject: O6 Chemistry

Language: ENG

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Description

Glucuronic Acid Free and Combined: Chemistry, Biochemistry, Pharmacology, and Medicine focuses on the study of glucuronic acid, particularly its physiological role in different fields.
Divided into three parts with nine chapters, the book contains the literature of authors who have incessantly conducted research on this kind of acid. The book starts with the discussion on the chemistry of free glucuronic acid and its derivatives, and then discusses the nature, characteristics, and properties of glucuronides and other known conjugates. The next part presents the occurrence and chemistry of glucuronic acid incorporated in animal, plant, and bacterial polysaccharides. This presentation is followed by the discussions on the biosynthesis of glucuronic acid as UDPglucuronic acid and its relationship with simple glucuronides. A summary of information of the enzymic hydrolysis of conjugates is then presented.
The succeeding chapters deal with the entry of glucuronic acid into general carbohydrate metabolism; the incorporation of glucuronic acid with the polysaccharides of living tissues; the pharmacological implications of glucuronic acid in drug detoxification; and the isolation and identification of steroid glucuronides.
The book is a primary source of data for readers interested in studying the nature, composition, functions, and uses of glucuronic acid.

Chapter

Front Cover

pp.:  1 – 4

Copyright Page

pp.:  5 – 12

List of Contributors

pp.:  6 – 8

Preface

pp.:  8 – 16

Table of Contents

pp.:  12 – 6

Introduction

pp.:  16 – 20

Part I: Chemistry

pp.:  20 – 202

Part II: Metabolism

pp.:  202 – 474

Part III: Biological Implications of Conjugation with Glucuronic Acid

pp.:  474 – 564

Author Index

pp.:  564 – 609

Subject Index

pp.:  609 – 649

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